Anti-BHLHE41, Biotin conjugated

Anti-BHLHE41, Biotin conjugated
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-PACO57543.50 50 µg -

9 - 20 Werktage*

293,00 €
 
BHLHE41 Antibody, Biotin conjugated is a IgG polyclonal antibody from Assay Genie with reactivity... mehr
Produktinformationen "Anti-BHLHE41, Biotin conjugated"
BHLHE41 Antibody, Biotin conjugated is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA applications. BHLHE41 Antibody, Biotin conjugated is a high quality polyclonal antibody for research use only.. Protein function: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes (PubMed:11278948, PubMed:14672706, PubMed:15193144, PubMed:15560782, PubMed:18411297, PubMed:19786558, PubMed:25083013). Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes (PubMed:25083013). Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity. Inhibits HNF1A-mediated transactivation of CYP1A2, CYP2E1 AND CYP3A11. [The UniProt Consortium]
Schlagworte: Anti-hDEC2, Anti-BHLHB3, Anti-bHLHb3, Anti-SHARP-1, Anti-bHLHe41, Anti-Class B basic helix-loop-helix protein 3, Anti-Class E basic helix-loop-helix protein 41, Anti-Enhancer-of-split and hairy-related protein 1
Hersteller: Assay Genie
Hersteller-Nr: PACO57543

Eigenschaften

Anwendung: ELISA
Antikörper-Typ: Polyclonal
Konjugat: Biotin
Wirt: Rabbit
Reaktivität: Human
Immunogen: Recombinant Human Class E basic helix-loop-helix protein 41 protein (185-285AA)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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