Anti-Beta-2 microglobulin, clone B2M-01 (Monoclonal) [Mouse]

Anti-Beta-2 microglobulin, clone B2M-01 (Monoclonal) [Mouse]
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
MON-MON1031A 100 µg - -

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275,00 €
 
MON 1031A reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I... mehr
Produktinformationen "Anti-Beta-2 microglobulin, clone B2M-01 (Monoclonal) [Mouse]"
MON 1031A reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes. Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes. Protein function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553). [The UniProt Consortium]
Schlagworte: Anti-CDABP0092, Mouse anti-Beta-2 microglobulin, clone B2M-01 (Monoclonal)
Hersteller: MONOSAN
Hersteller-Nr: MON1031A

Eigenschaften

Anwendung: ELISA, FC, ICC, IHC, IP, WB
Antikörper-Typ: Monoclonal
Klon: B2M-01
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: Human
Immunogen: Purified human beta2-microglobulin

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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