Anti-BCL10 (MALT-Lymphoma Marker)(B Cell CLL/lymphoma 10, B Cell leukemia/lymphoma 10, CARD-containi

Anti-BCL10 (MALT-Lymphoma Marker)(B Cell CLL/lymphoma 10, B Cell leukemia/lymphoma 10, CARD-containi
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
138496-AF.100 100 µg - -

3 - 19 Werktage*

659,00 €
 
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic... mehr
Produktinformationen "Anti-BCL10 (MALT-Lymphoma Marker)(B Cell CLL/lymphoma 10, B Cell leukemia/lymphoma 10, CARD-containi"
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFkappaB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1,14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Frozen & Formalin fixed paraffin embedded): 0.5-1ug/ml/30min @ RT, Flow Cytometry: 0.5-1ug/10e6 cells, Immunofluorescence: 1-2ug/ml, Western Blot: 0.5-1ug/ml, Immunoprecipitation: 1-2g/500ug protein lysate, Optimal dilutions to be determined by the researcher. Positive Control: WEHI-231 or Ramos cells or lymphoma, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hersteller: United States Biological
Hersteller-Nr: 138496-AF

Eigenschaften

Anwendung: ELISA, FC, IF, IHC, IP, WB
Antikörper-Typ: Monoclonal
Klon: BL10/411
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Format: Affinity Purified

Datenbank Information

UniProt ID : O95999 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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