Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG54823.200 200 µl - -

6 - 14 Werktage

444,00 €
Protein function: E1-like activating enzyme involved in the 2 ubiquitin- like systems required... mehr
Produktinformationen "Anti-ATG7"
Protein function: E1-like activating enzyme involved in the 2 ubiquitin- like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation. [The UniProt Consortium]
Schlagworte: Anti-ATG7, Anti-hAGP7, Anti-APG7L, Anti-APG7-like, Anti-Autophagy-related protein 7, Anti-ATG12-activating enzyme E1 ATG7, Anti-Ubiquitin-activating enzyme E1-like protein, Anti-Ubiquitin-like modifier-activating enzyme ATG7
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG54823200


Anwendung: ICC, IF, WB, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse (Erwartet: Rat)
Immunogen: KLH-conjugated synthetic peptide around aa. 494-523 from Human ATG7
Format: Ammonium Sulfate Precipitated

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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