Anti-Atg12 (Autophagy-related protein 12, Atg12, Apg12L, APG12-like)

Anti-Atg12 (Autophagy-related protein 12, Atg12, Apg12L, APG12-like)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A2298-75A2.100 100 µl - -

3 - 19 Werktage*

682,00 €
 
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic... mehr
Produktinformationen "Anti-Atg12 (Autophagy-related protein 12, Atg12, Apg12L, APG12-like)"
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (1,2). Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection and cancer (3). The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves an ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles (4-6). This conjugation reaction is mediated by the ubiquitin-E1-like enzyme Atg7 and the E2-like enzyme Atg10 (7,8). Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. , Immunoprecipitation: 1:100., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-Ubiquitin-like protein ATG12
Hersteller: United States Biological
Hersteller-Nr: A2298-75A2

Eigenschaften

Anwendung: IP, WB
Antikörper-Typ: Monoclonal
Klon: 10E4(D88H11)
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, monkey, mouse, rat
Immunogen: Synthetic peptide corresponding to residues surrounding Ser36 of human Atg12 protein (KLH- coupled).

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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