Anti-ATF4, clone S360A-24, ATTO 633 Conjugated

Anti-ATF4, clone S360A-24, ATTO 633 Conjugated
Aktion:

Gratis T-Shirt zu jeder Rockland-Bestellung über 500 €. 

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
200-360-W61 100 µg - -

1 - 9 Werktage

471,00 €
 
Anti-ATF4 Antibody was purified from concentrated tissue culture supernate by Protein G... mehr
Produktinformationen "Anti-ATF4, clone S360A-24, ATTO 633 Conjugated"
Anti-ATF4 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 85% identical to mouse, 86% identical to rat and <50% identical to ATF5. Will not cross react with ATF5. Protein function: Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes. [The UniProt Consortium]
Schlagworte: Anti-ATF4, Anti-CREB2, Anti-CREB-2, Anti-TaxREB67, Anti-DNA-binding protein TAXREB67, Anti-Activating transcription factor 4, Anti-cAMP-responsive element-binding protein 2, Anti-cAMP-dependent transcription factor ATF-4, Anti-Cyclic AMP-dependent transcr
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 200-360-W61

Eigenschaften

Anwendung: ELISA, IHC, WB
Antikörper-Typ: Monoclonal
Klon: S360A-24
Konjugat: ATTO 633
Wirt: Mouse
Reaktivität: Human, Rat
Immunogen: Fusion protein containing amino acids 25-327 of human ATF4.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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