Anti-ASAP1

Anti-ASAP1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-11-8069-25 25 µg -

3 - 11 Werktage*

134,00 €
 
ASAP (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1) or Development and... mehr
Produktinformationen "Anti-ASAP1"
ASAP (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1) or Development and differentiation-enhancing factor 1 or DDEF1 is an ADP-ribosylation factor (ARF) GTPase-activating protein with two known isoforms: ASAP1a and ASAP1b (125 and 126 kDa, respectively). ASAP contains a pleckstrin homology (PH) domain, a zinc finger motif, 3 ankyrin repeats, a proline-rich region containing several SH3 ligand motifs, and an SH3 domain. GTPase-activating property of ASAP1 is induced by phosphatidylinositol 4,5-biphosphate (PIP2) of the PH domain. ASAP1 plays an important role in cytoskeleton remodeling and regulation of membrane trafficking. ASAP1 acts as a proto-oncogene in breast cancer and other malignant tumors. ASAP is highly expressed in brain tissue. Protein function: Possesses phosphatidylinositol 4,5-bisphosphate- dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis. [The UniProt Consortium]
Schlagworte: Anti-DDEF1, Anti-ASAP1, Anti-DEF-1, Anti-PIP2-dependent ARF1 GAP, Anti-ARF GTPase-activating protein 1, Anti-Differentiation-enhancing factor 1, Anti-Development and differentiation-enhancing factor 1, Polyclonal Antibody to ASAP1
Hersteller: Abeomics
Hersteller-Nr: 11-8069-25

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: A partial length recombinant ASAP1 protein (amino acids 912-1115) was used as the immunogen for this antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-ASAP1"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen