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Anti-ARPC2

Anti-ARPC2
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-63458.60 60 µl - -

7 - 16 Werktage

119,00 €
E-AB-63458.120 120 µl - -

7 - 16 Werktage

211,00 €
E-AB-63458.200 200 µl - -

7 - 16 Werktage

367,00 €
 
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein... mehr
Produktinformationen "Anti-ARPC2"
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. Protein function: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947). [The UniProt Consortium]
Schlagworte: Anti-ARPC2, Anti-ARC34, Anti-p34-ARC, Anti-PRO2446, Anti-Arp2/3 complex 34 kDa subunit, Anti-Actin-related protein 2/3 complex subunit 2, ARPC2 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-63458-60µL

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Recombinant protein of human ARPC2

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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