Anti-ARNT

Anti-ARNT
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABD-8C10491.50 50 µg -

3 - 8 Werktage*

230,00 €
 
Custom conjugation services for this antibody as available (eg. labeling of Anti-ARNT with HRP.... mehr
Produktinformationen "Anti-ARNT"
Custom conjugation services for this antibody as available (eg. labeling of Anti-ARNT with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor(TM) 594, PE/iFluor(TM) 647, PE/iFluor(TM) 700, PE/iFluor(TM) 750, PE/Texas Red(R), PerCP, PerCP/Cy5.5. Small Molecules: Biotin. Traditional Dyes: FITC (Fluorescein), TRITC (Rhodamine), PacBlue, PacOrange, Cy3, Cy5. iFluor: 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7. mFluor: UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780. Protein function: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409). [The UniProt Consortium]
Schlagworte: Anti-ARNT, Anti-bHLHe2, Anti-BHLHE2, Anti-HIF1-beta, Anti-HIF-1-beta, Anti-ARNT protein, Anti-Hypoxia-inducible factor 1-beta, Anti-Dioxin receptor, nuclear translocator, Anti-Class E basic helix-loop-helix protein 2, ARNT Antibody
Hersteller: AAT Bioquest
Hersteller-Nr: 8C10491

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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