Protein function: Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6. [The UniProt Consortium]
Human (Erwartet: Orangutan, Gorilla, Chimpanzee, Northern White-cheeked Gibbon)
synthetic peptide. The epitope recognized by A301-961A-T maps to a region between residue 175 and 225 of human Rho guanine exchange factor (GEF) 16 using the numbering given in entry NP_055263.2 (GeneID 27237).