Anti-AQP4, clone 1A6

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-22025.20 20 µl -

7 - 16 Werktage*

72,00 €
E-AB-22025.60 60 µl -

7 - 16 Werktage*

142,00 €
E-AB-22025.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-22025.200 200 µl -

7 - 16 Werktage*

395,00 €
 
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function... mehr
Produktinformationen "Anti-AQP4, clone 1A6"
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Protein function: Forms a water-specific channel (PubMed:7559426, PubMed:8601457, PubMed:19383790). Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability. [The UniProt Consortium]
Schlagworte: Anti-WCH4, Anti-MIWC, Anti-AQP4, Anti-AQP-4, Anti-Aquaporin-4, Anti-Mercurial-insensitive water channel, AQP4 Monoclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-22025

Eigenschaften

Anwendung: WB, IHC (paraffin), IF
Antikörper-Typ: Monoclonal
Klon: 1A6
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
Immunogen: Synthetic Peptide
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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