Anti-Apoptosis inhibitor 5

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-39-2021-100 100 µg -

3 - 11 Werktage*

632,00 €
 
Many growth factors and cytokines act as cellular survival factors by preventing programmed cell... mehr
Produktinformationen "Anti-Apoptosis inhibitor 5"
Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death(apoptosis). Apoptosis inhibitor 5(API5) is an antiapoptotic factor which may have a role in protein assembly. The API5 gene to chromosome 11p12 based on an alignment of the API5 sequence with the genomic sequence It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription. Protein function: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. [The UniProt Consortium]
Schlagworte: Anti-FIF, Anti-API5, Anti-MIG8, Anti-API-5, Anti-AAC-11, Anti-Protein XAGL, Anti-Apoptosis inhibitor 5, Anti-Antiapoptosis clone 11 protein, Anti-Cell migration-inducing gene 8 protein, Anti-Fibroblast growth factor 2-interacting factor, Polyclonal Antibo
Hersteller: Abeomics
Hersteller-Nr: 39-2021

Eigenschaften

Anwendung: IHC (paraffin), IHC (frozen), ICC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of Human Apoptosis inhibitor 5(487-504aa KYSSNLGNFNYERSLQGK)(b), different from the related Mouse sequence by one amino acid.

Datenbank Information

UniProt ID : Q9BZZ5 | Passende Produkte
Gene ID : GeneID 8539 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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