Anti-APE-1 (Apurinic Endonuclase Factor 1)

Anti-APE-1 (Apurinic Endonuclase Factor 1)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A2298-74E1.40 40 µg - -

3 - 19 Werktage*

419,00 €
 
APE1 repairs oxidative DNA damages in vitro. It may also play a role in preventing cell death by... mehr
Produktinformationen "Anti-APE-1 (Apurinic Endonuclase Factor 1)"
APE1 repairs oxidative DNA damages in vitro. It may also play a role in preventing cell death by suppressing mutations. APE1 removes the blocking groups from the 3'-termini of breaks in the DNA strand generated by ionizing radiation or bleomycin. APE1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effects of oxidizing agents. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.05-0.2ug/ml, Western Blot: 0.5-1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-APEN, Anti-REF-1, EC=3.1.-.-, Anti-APEX1, EC=4.2.99.18, Anti-APEX nuclease, Anti-Redox factor-1, Anti-AP endonuclease 1, Anti-Apurinic-apyrimidinic endonuclease 1, Anti-DNA-(apurinic or apyrimidinic site) lyase
Hersteller: United States Biological
Hersteller-Nr: A2298-74E1

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Synthetic peptide (KLH). within residues 200-250 of human APE1 protein (Swiss Prot: P27695).
Reinheit: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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