Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32132 100 µg - -

3 - 10 Werktage

503,00 €
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Arf-GAP domain and FG repeats-containing... mehr
Produktinformationen "Anti-AGFG1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Arf-GAP domain and FG repeats-containing protein 1 is aprotein that in humans is encoded by the AGFG1 gene. AGFG1 is located to 2q36.3. The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. Protein function: Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. [The UniProt Consortium]
Schlagworte: Anti-HRB, Anti-AGFG1, Anti-Rev-interacting protein, Anti-HIV-1 Rev-binding protein, Anti-Nucleoporin-like protein RIP, Anti-Rev/Rex activation domain-binding protein, Anti-Arf-GAP domain and FG repeat-containing protein 1, AGFG1 Antibody
Hersteller-Nr: R32132


Anwendung: WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Rat
Immunogen: Amino acids AKRKQEEKHLKMLRDMTGLPHNRK of human AGFG1 were used as the immunogen for the AGFG1 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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