Anti-ADORA2B

This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. Protein function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [The UniProt Consortium]