Anti-ADAMTS4

Anti-ADAMTS4
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32650 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. ADAMTS4, A disintegrin and... mehr
Produktinformationen "Anti-ADAMTS4"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4, is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. Protein function: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-, -Ala-393' site. [The UniProt Consortium]
Schlagworte: Anti-ADMP-1, Anti-ADAMTS4, Anti-ADAM-TS4, Anti-KIAA0688, Anti-ADAMTS-4, Anti-ADAM-TS 4, EC=3.4.24.82, Anti-Aggrecanase-1, Anti-A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAMTS4 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R32650

Eigenschaften

Anwendung: WB, IHC (paraffin), ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Amino acids 813-837 (TPQDWLHRRAQILEILRRRPWAGRK) from the human protein
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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