Anti-Active Rac-GTP, monoclonal

Anti-Active Rac-GTP, monoclonal
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NB-26903 30 µl - -

3 - 16 Werktage*

669,00 €
 
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50%... mehr
Produktinformationen "Anti-Active Rac-GTP, monoclonal"
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it inactive.Currently the activation of Rac proteins is assayed with the binding of GTP-bound Rac to the p21-binding domain (PBD) of p21-activated protein kinase (PAK). This method is based on the observation that the active, GTP-bound Rac could bind to the PBD of PAK. However, the reproducibility of this method is poor. This is partially due to the relatively quick hydrolysis of GTP to GDP during the assay procedure, and the low binding affinity of PBD to Rac-GTP.
Schlagworte: Anti-MIG5, Anti-RAC1, Anti-TC25, Anti-p21-Rac1, Anti-Ras-like protein TC25, Anti-Cell migration-inducing gene 5 protein, Anti-Ras-related C3 botulinum toxin substrate 1
Hersteller: NewEast Biosciences
Hersteller-Nr: 26903

Eigenschaften

Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Konjugat: No
Wirt: Mouse
Reaktivität: Vertebrates
Immunogen: Recombinant full length protein of active Rac1
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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