Anti-ACTH (Adrenocorticotrophic Hormone) (C-Terminus) Monoclonal Antibody (Clone: CLIP/1418)

Anti-ACTH (Adrenocorticotrophic Hormone) (C-Terminus) Monoclonal Antibody (Clone: CLIP/1418)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-36-2959-20 20 µg -

3 - 11 Werktage*

287,00 €
ABE-36-2959-100 100 µg -

3 - 11 Werktage*

661,00 €
 
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior... mehr
Produktinformationen "Anti-ACTH (Adrenocorticotrophic Hormone) (C-Terminus) Monoclonal Antibody (Clone: CLIP/1418)"
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to CLIP (aa25-39 of ACTH), does not react with Synacthen (aa1-24 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes throµgh extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH. ' Protein function: [Corticotropin]: Stimulates the adrenal glands to release cortisol. [The UniProt Consortium]
Schlagworte: Anti-POMC, Anti-ACTH (Adrenocorticotrophic Hormone) (C-Terminus) Monoclonal Antibody (Clone: CLIP/1418)
Hersteller: Abeomics
Hersteller-Nr: 36-2959

Eigenschaften

Anwendung: ELISA
Antikörper-Typ: Monoclonal
Klon: CLIP/1418
Konjugat: No
Wirt: Mouse
Reaktivität: Human
Immunogen: Synthetic peptide corresponding to aa25-39 of human ACTH (NGAEDESAEAFPLEF)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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