Anti-ABHD12

Anti-ABHD12
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA026866.25 25 µl -

7 - 10 Werktage*

335,00 €
ATA-HPA026866.100 100 µl -

7 - 10 Werktage*

446,00 €
 
Protein function: Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of... mehr
Produktinformationen "Anti-ABHD12"
Protein function: Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (PubMed:25290914, PubMed:30237167, PubMed:30420694, PubMed:30720278, PubMed:30643283). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system. Also able to hydrolyze oxidized phosphatidylserine, oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal (PubMed:30643283). Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways (PubMed:22969151, PubMed:24027063). Has a strong preference for very-long-chain lipid substrates, substrate specificity is likely due to improved catalysis and not improved substrate binding (PubMed:30237167). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 95%
Schlagworte: Anti-hABHD12, Anti-Monoacylglycerol lipase ABHD12, Anti-Lysophosphatidylserine lipase ABHD12, Anti-2-arachidonoylglycerol hydrolase ABHD12, Anti-Abhydrolase domain-containing protein 12, Anti-Oxidized phosphatidylserine lipase ABHD12
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA026866

Eigenschaften

Anwendung: IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ALILESPFTN IREEAKSHPF SVIYRYFPGF DWFFLDPITS SGIKFANDEN VKHISCPLLI LHAEDDPVVP FQLGRKLYSI AAPARSFRDF KVQFVPFHSD LGYRHKYIYK SPELPRILRP (ATA-APrEST71710)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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