Produkte von LC Laboratories

LC Laboratories

LC Laboratories aus Woburn, Massachusetts liefert seit 1980 Small Molecules für die Forschung. Zahlreiche Hersteller von Reagenzien verkaufen die hochwertigen Produkte von LC Laboratories unter ihrem eigenen Label. Wenn Sie im Bereich Signaltransduktion, Onkologie oder anderer präklinischer Forschung unterwegs sind, haben Sie sich wahrscheinlich von Anfang an, bewusst oder unbewusst, auf LC Labs-Produkte verlassen.

Mehr Informationen unter: www.lclabs.com

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SB431542, Free Base
SB431542, Free Base

Artikelnummer: LC-S-7800_10mg

Soluble in DMSO. SB-431542 selectively inhibited Smad3 phosphorylation, with an IC50 of 94 nM. It also blocked TGF-beta1-induced nuclear Smad3 localization. Laping N.J., et al. 'Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor...
Schlagworte: SB 431542, 4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamide hydrate,...
Anwendung: Smad3 phosphorylation inhibitor, TGFBR1/ALK4/ALK7 kinase inhibitor
CAS 301836-41-9
MW: 384.39 D
ab 93,00 €
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Afatinib, Free Base (BIBW-2992, Giotrif, Gilotrif, Tovok, Tomtovok, CAS 850140-72-6, CAS 439081-18-2
Afatinib, Free Base (BIBW-2992, Giotrif, Gilotrif, Tovok,...

Artikelnummer: LC-A-8644_1g

Soluble in DMSO at 200 mg/mL, soluble in ethanol at 25 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 50-100 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Anwendung: Tyrosine kinase inhibitor
CAS 850140-72-6
MW: 485,94 D
ab 91,00 €
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Bosutinib, Free Base (SKI-606, Bosulif, CAS 380843-75-4), >99%
Bosutinib, Free Base (SKI-606, Bosulif, CAS 380843-75-4),...

Artikelnummer: LC-B-1788_100mg

Soluble in DMSO at 200 mg/mL, soluble in ethanol at 25 mg/mL with warming, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-50 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Schlagworte: SKI 606, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile
Anwendung: c-Src and Abl inhibitor
CAS 380843-75-4
MW: 530,45 D
ab 83,00 €
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Birinapant, Free Base (TL-32711, CAS 1260251-31-7), >99%
Birinapant, Free Base (TL-32711, CAS 1260251-31-7), >99%

Artikelnummer: LC-B-9135_10mg

Soluble in DMSO
Schlagworte: TL-32711,...
Anwendung: Antineoplastic, XIAP / cIAP1 inhibitor
CAS 1260251-31-7
MW: 806,94 D
ab 108,00 €
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Celecoxib (Celebrex, Celebra, Celocoxib, Celecox, Onsenal, Solexa, SC-58635, YM-177, 4-[5-(4-Methylp
Celecoxib (Celebrex, Celebra, Celocoxib, Celecox,...

Artikelnummer: LC-C-1502_1g

Soluble in DMSO at 200 mg/mL, soluble in ethanol at 100 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-50 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Schlagworte: Celebra, Celebrex(TM), Onsenal, SC-58635, Xilebao, YM-177,...
Anwendung: COX-2 inhibitor
CAS 169590-42-5
MW: 381,37 D
ab 88,00 €
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Cabazitaxel (Jevtana, RPR-116258, Taxoid XRP6258, TXD-258, XRP-6258, CAS 183133-96-2), >99%
Cabazitaxel (Jevtana, RPR-116258, Taxoid XRP6258,...

Artikelnummer: LC-C-2581_100mg

Soluble in DMSO at 100 mg/mL, soluble in ethanol at 50 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 1-2 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Schlagworte: beta-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-hydroxy-benzenepropanoic acid,...
Anwendung: Tubulin depolymerization inhibitor
CAS 183133-96-2
MW: 835,93 D
ab 90,00 €
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Cabozantinib, Free Base (BMS-907351, Cometriq, XL-184, CAS 849217-68-1), >99%
Cabozantinib, Free Base (BMS-907351, Cometriq, XL-184,...

Artikelnummer: LC-C-8901_100mg

Soluble in DMSO
Schlagworte: BMS-907351, Cabozantinib, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
Anwendung: Pan tyrosine kinase inhibitor
CAS 849217-68-1
MW: 501,51 D
ab 86,00 €
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Dacomitinib, Free Base (PF299, PF299804, PF00299804, CAS 1110813-31-4), >99%
Dacomitinib, Free Base (PF299, PF299804, PF00299804, CAS...

Artikelnummer: LC-D-3700_100mg

Soluble in DMSO
Schlagworte: Dacomitinib, PF299, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-(2E)-butenamide
Anwendung: pan-erbB receptor tyrosine kinase inhibitor
CAS 1110813-31-4
MW: 469,94 D
ab 80,00 €
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Daporinad, Free Base (APO866, FK866, K22.175, WK175, CAS 658084-64-1), >99%
Daporinad, Free Base (APO866, FK866, K22.175, WK175, CAS...

Artikelnummer: LC-D-5600_10mg

Soluble in DMSO
Schlagworte: K 22.175, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2E-propenamide
Anwendung: NAMPT inhibitor
CAS 658084-64-1
MW: 391,51 D
ab 106,00 €
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Ibrutinib, Free Base
Ibrutinib, Free Base

Artikelnummer: LC-I-3311_200mg

Solubility: Soluble in DMSO at 200 mg/mL, soluble in ethanol at 25 mg/mL with slight warming. Ibrutinib, also known as PCI-32765, is a selective and irreversible inhibitor of the enzyme Bruton's tyrosine kinase (BTK). It inhibited BTK potently, with an IC50 of 0.72 nM in enzymology assays and with an IC50 of 10 nM...
Schlagworte: CRA-032765, PCI-32765, PCI-32765-00
Anwendung: Selective, irreversible Bruton's tyrosine kinase (BTK) inhibitor
CAS 936563-96-1
MW: 440.5 D
ab 85,00 €
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Lapatinib, Free Base (GSK 572016, GW-572016, GW 572016X, Tykerb, Tyverb, CAS 231277-92-2), >99%
Lapatinib, Free Base (GSK 572016, GW-572016, GW 572016X,...

Artikelnummer: LC-L-4899_500mg

Soluble in DMSO at 200 mg/mL, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 1-10 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Schlagworte: GSK572016, GW 572016, Tyverb,...
Anwendung: EGFR / HER2 inhibitor
CAS 231277-92-2
MW: 581,06 D
ab 76,00 €
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Neratinib, Free Base
Neratinib, Free Base

Artikelnummer: LC-N-6404_100mg

Solubility: Soluble in DMSO at 2 mg/mL with warming, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 5-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility. Neratinib, also known as HKI-272, is considered to...
Schlagworte: HKI-272
Anwendung: EGFR/ ERBB2 inhibitor
CAS 698387-09-6
MW: 557,04 D
ab 175,00 €
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