Produkte von Innaxon
Innaxon ist ein Unternehmen mit Sitz in Tewkesbury, Vereinigtes Königreich, das sich auf angeborene Immunität, Toll-like Rezeptor (TLR)-Agonisten und niedermolekulare Inhibitoren konzentriert. Innaxon entwickelt und produziert definierte "Immunoceuticals" von höchster Aktivität und Reinheit für präklinische Forschungs- und Entwicklungsanwendungen für Impfstoffadjuvantien und Immuntherapie. Die einzigartigen biologischen und synthetischen TLR-Liganden von Innaxon sind gut charakterisierte und wirksame biologische Reaktionsmodifikatoren für unangemessene oder unverhältnismäßige Immunreaktionen.
Mehr Informationen unter: www.adipogen.com/innaxon
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Lipid A from S. minnesota R595 (Re) TLRpure Sterile Solution
Artikelnummer: IAX-100-001-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
| Schlagworte: | Lipid A derived from S. minnesota strain R595 (Re) TLRpure LPS (biosynthetic) |
| Anwendung: | TLR4 activator |
ab 156,00 €
![Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution](https://www.biomol.com/media/image/67/fb/15/IAX-100-002-M001_200x200.png "Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution")
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re)...
Artikelnummer: IAX-100-002-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
| Schlagworte: | Monophosphoryl Lipid A [MPLA] derived from S. minnesota R595 (Re) TLRpure LPS (biosynthetic) |
| Anwendung: | TLR4 activator |
ab 211,00 €
LPS from S. abortus equi (S-form) Biotin TLRpure Sterile...
Artikelnummer: IAX-100-009B-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Biotinylated Lipopolysaccharide (LPS) from S. abortus equi, S-type (smooth/wild-type) LPS |
| Anwendung: | TLR4 activator |
ab 184,00 €
LPS from E. coli EH100 (Ra) TLRpure Sterile Solution
Artikelnummer: IAX-100-010-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from E. coli strain EH100 (Ra), R-type (rough/mutant) LPS |
| Anwendung: | TLR4 activator |
ab 175,00 €
LPS from S. minnesota R60 (Ra) TLRpure Sterile Solution
Artikelnummer: IAX-100-016-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from S. minnesota strain R60 (Ra), R-type (rough/mutant) LPS |
| Anwendung: | TLR4 activator |
ab 197,00 €
LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution
Artikelnummer: IAX-100-017-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from S. minnesota strain R5 (Rc), R-type (rough/mutant) LPS |
| Anwendung: | TLR4 activator |
ab 175,00 €
LPS from S. minnesota R3 (Rd2) TLRpure Sterile Solution
Artikelnummer: IAX-100-021-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from S. minnesota strain R3 (Rd2), R-type (rough/mutant) LPS |
| Anwendung: | TLR4 activator |
ab 175,00 €
Neutral-ODN (Control for iODNs) Endotoxin-free (sterile)
Artikelnummer: IAX-200-202-M001
Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 1585 (Cat. No.: IAX-200-003). For negative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
| Anwendung: | Negative Control for ODN 1585 (IAX-200-003) |
| MW: | 4821 D |
ab 179,00 €
ODN 2243 (Control for ODN 2216) Endotoxin-free (sterile)
Artikelnummer: IAX-200-205-C100
Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 2216 (Cat. No.: IAX-200-005). For negative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
| Anwendung: | Negative Control for ODN 2216 (IAX-200-005) |
| MW: | 6684 D |
179,00 €
ODN 2137 (Control for ODN 2006) Endotoxin-free (sterile)
Artikelnummer: IAX-200-206-C100
Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 2006 (Cat. No.: IAX-200-006). For inegative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
| Anwendung: | Negative Control for ODN 2006 (IAX-200-006) |
| MW: | 6684 D |
179,00 €
IAXO-102 (CD14/TLR4 Antagonist) (synthetic)
Artikelnummer: IAX-600-002-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Schlagworte: | Methyl 6-deoxy-6-amino-2,3-di-O-tetradecyl-?-D-glucopyranoside |
| Anwendung: | CD14/TLR4 Antagonist |
| CAS | 1115270-63-7 |
| MW: | 585.94 D |
347,00 €
IAXO-103 (CD14/TLR4 Antagonist) (synthetic)
Artikelnummer: IAX-600-003-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Schlagworte: | N-(3,4-bis-Tetradecyloxy-benzyl)-N-cyclopentyl-N,N-dimethylammonium iodide |
| Anwendung: | CD14/TLR4 Antagonist |
| CAS | 1202208-36-3 |
| MW: | 755.98 D |
347,00 €