Produkte von Indigo Biosciences

Indigo

Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.

Mehr Informationen unter: www.indigobiosciences.com

Zu den Katalogen von Indigo Biosciences

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PPARgamma (human) Reporter Assay Kit
PPARgamma (human) Reporter Assay Kit

Artikelnummer: IB-IB00101

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
Schlagworte: NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma
Anwendung: Functional activity screening
Spezies-Reaktivität: human
ab 1.448,00 €
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GR Bioassay for Environmental Sample Monitoring
GR Bioassay for Environmental Sample Monitoring

Artikelnummer: IB-EM00201

This Glucocorticoid Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to ER Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist Dexamethasone, Luciferase...
Schlagworte: GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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ER Bioassay for Environmental Sample Monitoring
ER Bioassay for Environmental Sample Monitoring

Artikelnummer: IB-EM00431

This Estrogen Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to ER Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist 17beta-estradiol (E2),...
Schlagworte: ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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MR Bioassay for Environmental Sample Monitoring
MR Bioassay for Environmental Sample Monitoring

Artikelnummer: IB-EM00501

This Mineralocorticoid Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to MR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist Aldosterone, Luciferase...
Schlagworte: MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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AR Bioassay for Environmental Sample Monitoring
AR Bioassay for Environmental Sample Monitoring

Artikelnummer: IB-EM03001

This Androgen Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to AR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, Luciferase Detection Reagent, and a cell culture-ready...
Schlagworte: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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AhR Bioassay for Environmental Sample Monitoring
AhR Bioassay for Environmental Sample Monitoring

Artikelnummer: IB-EM06001

This Aryl Hydrocarbon Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to AhR Reporter Cells, this kit includes are two optimized media for use during cell culture and in diluting the user's test samples, Luciferase Detection...
Schlagworte: AhR, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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GM-CSFR Reporter Assay System (Human)
GM-CSFR Reporter Assay System (Human)

Artikelnummer: IB-IB30001

This Granulocyte-Macrophage Colony-Stimulating Factor Receptor (GM-CSFR) assay kit is an all-inclusive luciferase reporter assay system that includes, in addition to GM-CSFR Reporter Cells, optimized culture medium for use in reviving the cryopreserved cells, a culture medium for use in preparing test sample...
Schlagworte: CD116, CSF2R, CDw116, CSF2RA, GMR-alpha, GMCSFR-alpha, GM-CSF-R-alpha, Granulocyte-macrophage colony-stimulating factor...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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GM-CSFR Reporter Assay System (Human)
GM-CSFR Reporter Assay System (Human)

Artikelnummer: IB-IB30002

This Granulocyte-Macrophage Colony-Stimulating Factor Receptor (GM-CSFR) assay kit is an all-inclusive luciferase reporter assay system that includes, in addition to GM-CSFR Reporter Cells, optimized culture medium for use in reviving the cryopreserved cells, a culture medium for use in preparing test sample...
Schlagworte: CD116, CSF2R, CDw116, CSF2RA, GMR-alpha, GMCSFR-alpha, GM-CSF-R-alpha, Granulocyte-macrophage colony-stimulating factor...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
3.802,00 €
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MR Reporter Assay System (Mouse)
MR Reporter Assay System (Mouse)

Artikelnummer: IB-M00501

This Mouse Mineralocorticoid Receptor (MR) assay kit is an all-inclusive mouse MR reporter assay system that includes, in addition to mouse MR Reporter Cells, two optimized media for use during cell culture and (optionally) in diluting the test samples, a reference agonist, Luciferase Detection Reagent, a cell...
Schlagworte: MR, Mlr, Nr3c2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2
Anwendung: Functional activity screening
Spezies-Reaktivität: mouse
1.448,00 €
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ERalpha (human) Reporter Assay Kit
ERalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00401

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
Anwendung: Functional activity screening
Spezies-Reaktivität: human
ab 1.448,00 €
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Nrf2 (Human) Reporter Assay System
Nrf2 (Human) Reporter Assay System

Artikelnummer: IB-IB10001

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
Schlagworte: NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
ab 1.448,00 €
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PPARalpha (human) Reporter Assay Kit
PPARalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00111

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include...
Schlagworte: NR1C1, PPARA, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha
Anwendung: Functional activity screening
Spezies-Reaktivität: human
ab 1.448,00 €
Bewerten
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