Produkte von Indigo Biosciences

Indigo

Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, PA von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich Kernrezeptoren, die eine wichtige Klasse von therapeutischen Wirkstoffzielen darstellen. Hierbei stellen quantitative Aktivitäts-Assays noch immer eine besondere Herausforderung für die Biotechnologie dar. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.

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FXR (human) Reporter Assay Kit
FXR (human) Reporter Assay Kit

Artikelnummer: IB-IB00602

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: BAR, NR1H4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,...
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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VDR (human) Reporter Assay Kit
VDR (human) Reporter Assay Kit

Artikelnummer: IB-IB00702

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human vitamin D receptor (NR1I1), a ligand-dependent transcription factor commonly referred to as VDR. INDIGO's reporter cells include the luciferase reporter gene functionally linked...
Schlagworte: VDR, NR1I1, Vitamin D3 receptor, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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RXRalpha (human) Reporter Assay Kit
RXRalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00802

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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RXRbeta (human) Reporter Assay Kit
RXRbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB00812

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor beta (NR2B2), a ligand-dependent transcription factor commonly referred to as RXRB or RXRbeta. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRB, NR2B2, Retinoid X receptor beta, Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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RXRgamma (human) Reporter Assay Kit
RXRgamma (human) Reporter Assay Kit

Artikelnummer: IB-IB00822

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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RXR (human) Reporter Assays Panel
RXR (human) Reporter Assays Panel

Artikelnummer: IB-IB00831-32P

INDIGO's panel of RXR reporter assays utilizes non-human mammalian cells engineered to individually express human retinoic acid receptors, RXRalpha (NR2B1), RXRbeta (NR2B2), or RXRgamma (NR2B3). INDIGO's RXR reporter cells include the luciferase reporter gene functionally linked to a responsive promoter. Thus,...
Anwendung: Functional activity screening
Reaktivität: Human
1.422,00 €
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CAR3 (human) Reporter Assay Kit
CAR3 (human) Reporter Assay Kit

Artikelnummer: IB-IB00902

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human constitutive androstane receptor, isoform 3 (NR1I3), a ligand-dependent transcription factor commonly referred to as CAR3. These reporter cells utilize a modified...
Schlagworte: CAR, NR1I3, Constitutive active response, Orphan nuclear receptor MB67, Constitutive androstane receptor, Constitutive...
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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TRalpha (human) Reporter Assay Kit
TRalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB01002

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human thyroid hormone receptor alpha (NR1A1), a ligand-dependent transcription factor commonly referred to as TRalpha. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: THRA, EAR7, EAR-7, c-erbA-1, c-erbA-alpha, V-erbA-related protein 7, Thyroid hormone receptor alpha, Nuclear receptor...
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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TRbeta (human) Reporter Assay Kit
TRbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB01102

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human thyroid hormone receptor beta (NR1A2), a ligand-dependent transcription factor commonly referred to as TRbeta. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: THRB, ERBA2, c-erbA-2, c-erbA-beta, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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TR (human) Reporter Assays Panel
TR (human) Reporter Assays Panel

Artikelnummer: IB-IB01201-48P

INDIGO's panel of TR reporter assays utilizes non-human mammalian cells engineered to express human thyroid hormone receptors alpha (NR1A3) and beta (NR1A2), ligand-dependent transcription factors commonly referred to as TRalpha and TRbeta. INDIGO's TR reporter cells include the luciferase reporter gene functionally...
Schlagworte: thyroid hormone receptor alpha (NR1A1), thyroid hormone receptor beta (NR1A2), Tralpha, TRbeta
Anwendung: Functional activity screening
Reaktivität: Human
1.422,00 €
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RARgamma (human) Reporter Assay Kit
RARgamma (human) Reporter Assay Kit

Artikelnummer: IB-IB02002

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor gamma (NR1B3), a ligand-dependent transcription factor commonly referred to as RARG or RARgamma. INDIGO's reporter cells include the luciferase...
Schlagworte: RARG, NR1B3, RAR-gamma, Retinoic acid receptor gamma, Nuclear receptor subfamily 1 group B member 3
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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RARbeta (human) Reporter Assay Kit
RARbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB02102

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor, beta (NR1B2), a ligand-dependent transcription factor commonly referred to as RARB or RARbeta. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: HAP, RARB, RAR-beta, RAR-epsilon, HBV-activated protein, Retinoic acid receptor beta, Nuclear receptor subfamily 1 group B...
Anwendung: Functional activity screening
Reaktivität: Human
2.837,00 €
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