Produkte von Indigo Biosciences

Indigo

Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.

Mehr Informationen unter: www.indigobiosciences.com

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NF-kappaB (Human) Reporter Assay System
NF-kappaB (Human) Reporter Assay System

Artikelnummer: IB-IB09001-32

Anwendung: Functional activity screening
Spezies-Reaktivität: human
ab 1.448,00 €
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AhR (human) Assay Kit
AhR (human) Assay Kit

Artikelnummer: IB-IB06001

INDIGO's Aryl Hydrocarbon Receptor (AhR) Reporter Cells include the luciferase reporter gene functionally linked to an AhR-responsive promoter. Thus, quantifying changes in luciferase expression in the treated reporter cells provides a sensitive surrogate measure of the changes in AhR activity. The principle...
Schlagworte: Aryl Hydrocarbon Receptor (human) Assay Kit, AHR, AhR, BHLHE76, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E...
Anwendung: Functional activity screening
ab 1.448,00 €
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LXRb Reporter Assay System (dog)
LXRb Reporter Assay System (dog)

Artikelnummer: IB-D00301

Schlagworte: Nuclear receptor subfamily 1 group H member 2
Anwendung: Functional activity screening
Spezies-Reaktivität: dog
1.448,00 €
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LXRa Reporter Assay System (dog)
LXRa Reporter Assay System (dog)

Artikelnummer: IB-D00311

Schlagworte: Nuclear receptor subfamily 1 group H member 3
Anwendung: Functional activity screening
Spezies-Reaktivität: dog
1.448,00 €
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INSRb Reporter Assay System (human)
INSRb Reporter Assay System (human)

Artikelnummer: IB-IB28001

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
Schlagworte: INSR, EC=2.7.10.1
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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INSRb Reporter Assay System (human)
INSRb Reporter Assay System (human)

Artikelnummer: IB-IB28002

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
Schlagworte: INSR, EC=2.7.10.1
Anwendung: Functional activity screening
Spezies-Reaktivität: human
3.802,00 €
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IGF-1R Reporter Assay System (human)
IGF-1R Reporter Assay System (human)

Artikelnummer: IB-IB29001

Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of...
Schlagworte: IGF1R, EC=2.7.10.1
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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IGF-1R Reporter Assay System (human)
IGF-1R Reporter Assay System (human)

Artikelnummer: IB-IB29002

Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of...
Schlagworte: IGF1R, EC=2.7.10.1
Anwendung: Functional activity screening
Spezies-Reaktivität: human
3.802,00 €
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ADRA1A Reporter Assay System (human)
ADRA1A Reporter Assay System (human)

Artikelnummer: IB-IB31001

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1A (ADRA1A). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1A. In addition to ADRA1A Reporter Cells, this kit...
Schlagworte: ADRA1A, ADRA1C, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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ADRA1A Reporter Assay System (human)
ADRA1A Reporter Assay System (human)

Artikelnummer: IB-IB31002

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1A (ADRA1A). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1A. In addition to ADRA1A Reporter Cells, this kit...
Schlagworte: ADRA1A, ADRA1C, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
3.803,00 €
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Human M-CSFR Reporter Assay System
Human M-CSFR Reporter Assay System

Artikelnummer: IB-IB30201

Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
Schlagworte: Anti-FMS, Anti-CSF1R, Anti-CD115, Anti-CSF-1R, Anti-CSF-1-R, Anti-M-CSF-R, EC=2.7.10.1, Anti-CSF-1 receptor,...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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Human M-CSFR Reporter Assay System
Human M-CSFR Reporter Assay System

Artikelnummer: IB-IB30202

Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
Schlagworte: Anti-FMS, Anti-CSF1R, Anti-CD115, Anti-CSF-1R, Anti-CSF-1-R, Anti-M-CSF-R, EC=2.7.10.1, Anti-CSF-1 receptor,...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
3.802,00 €
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