Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
Mehr Informationen unter: www.dimabio.com
Für die Filterung wurden keine Ergebnisse gefunden!
Human CD27 Protein, mFc-His Tag
Artikelnummer: DIM-PME100013.10
Recombinant human CD27 protein with C-terminal mouse Fc and 6×His tag. CD27(Ala20-Arg191) mFc(Pro99-Lys330) 6×His, Protein function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. [The UniProt Consortium]
| Schlagworte: | CD27, TNFRSF7, S152, T14, Tp55 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 65-72 kD |
ab 140,00 €
Human CD40 Protein, mFc-His Tag
Artikelnummer: DIM-PME100015.10
Recombinant human CD40 protein with C-terminal mouse Fc and 6×His tag. CD40(Glu21-Arg193) mFc(Pro99-Lys330) 6×His, Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin...
| Schlagworte: | CD40, Bp50, CDW40, MGC9013, TNFRSF5, p50 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 68 kD |
ab 120,00 €
Human CD48 Protein, mFc-His Tag
Artikelnummer: DIM-PME100016.10
Recombinant human CD48 protein with C-terminal mouse Fc and 6×His. CD48(Gln27-Ser220) mFc(Pro99-Lys330) 6×His, Protein function: Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. [The UniProt Consortium]
| Schlagworte: | CD48, BCM1, SLAMF2, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 69-72 kD |
ab 133,00 €
Human CTLA-4 Protein, mFc-His Tag
Artikelnummer: DIM-PME100017.10
Recombinant human CTLA-4 protein with C-terminal mouse Fc and 6×His tag. CTLA-4(Lys36-Asp161) mFc(Pro99-Lys330) 6×His tag, Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger...
| Schlagworte: | CTLA4, CD152 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 54 kD |
ab 140,00 €
Human GITR Protein, hFc-His tag
Artikelnummer: DIM-PME100018.10
Recombinant human GITR protein with C-terminal human Fc and 6×His tag. GITR(Gln26-Pro162) hFc(Glu99-Ala330) 6×His, Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated...
| Schlagworte: | AITR, GITR, TNFRSF18, CD357 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 51-52 kD |
ab 140,00 €
Human GITR Protein, mFc-His tag
Artikelnummer: DIM-PME100019.10
Recombinant human GITR protein with C-terminal mouse Fc and 6×His tag. GITR(Gln26-Pro162) mFc(Pro99-Lys330) 6×His, Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated...
| Schlagworte: | AITR, GITR, TNFRSF18, CD357 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 50-52 kD |
ab 114,00 €
Human GITR Ligand Protein, mFc-His tag
Artikelnummer: DIM-PME100020.10
Recombinant human GITR Ligand protein with N-terminal mouse Fc and C-terminal 6×His tag. mFc(Pro99-Lys330) GITR Ligand(Gln50-Ser177) 6×His, Protein function: Cytokine that binds to TNFRSF18/AITR/GITR (PubMed:14521928, PubMed:14647196). Regulates T-cell responses (PubMed:14647196). Can function as costimulator and...
| Schlagworte: | TNFSF18, AITRL, TL6, hGITRL, GITR Ligand |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 46-53 kD |
ab 124,00 €
Human OX40L Protein, mFc-His tag
Artikelnummer: DIM-PME100021.10
Recombinant human OX40L protein with N-terminal mouse Fc and C-terminal 6×His tag. mFc(Pro99-Lys330) OX40 Ligand(Gln51-Leu183) 6×His, Protein function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. [The UniProt Consortium]
| Schlagworte: | OX40L, TNFSF4, CD252, Glycoprotein Gp34, TXGP1, CD134 ligand, CD134L |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 44.0 kD |
ab 140,00 €
Human OX40 Protein, hFc-His tag
Artikelnummer: DIM-PME100022.10
Recombinant human OX40 protein with C-terminal human Fc and 6×His tag. OX40(Leu29-Ala214) hFc(Glu99-Ala330) 6×His tag, Protein function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. [The UniProt Consortium]
| Schlagworte: | TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 47.2 kD |
ab 140,00 €
Human SLAMF1 Protein, mFc-His tag
Artikelnummer: DIM-PME100024.10
Recombinant human SLAMF1 protein with C-terminal mouse Fc and 6×His tag. SLAMF1(Ala21-Pro237) mFc(Pro99-Lys330) 6×His tag, Protein function: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the...
| Schlagworte: | SLAMF1, CD150, CDw150, SLAM, IPO-3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 51.8 kD |
ab 140,00 €
Human PD-1 Protein, mFc-His tag
Artikelnummer: DIM-PME100025.10
Recombinant human PD-1 protein with C-terminal mouse Fc and 6×His tag. PD-1(Phe24-Val170) mFc(Pro99-Lys330) 6×His tag, Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals...
| Schlagworte: | PDCD1, PD1, CD279, SLEB2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 43.5 kD |
ab 140,00 €
Human ICOS Protein, mFc-His tag
Artikelnummer: DIM-PME100026.10
Recombinant human ICOS protein with C-terminal mouse Fc and 6×His tag. ICOS(Glu21-Lys140) mFc(Pro99-Lys330) 6×His tag, Protein function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and...
| Schlagworte: | ICOS, CD278, AILIM, Inducible T-cell costimulator |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 41.1 kD |
ab 133,00 €