Produkte von Chimerigen Laboratories

Chimerigen

Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.

Mehr Informationen unter: www.adipogen.com/chimerigen

Zu den Katalogen von Chimerigen Laboratories

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IL-17A (human):Fc (human) (rec.) (non-lytic)
IL-17A (human):Fc (human) (rec.) (non-lytic)

Artikelnummer: CHI-HF-22017A-C050

Interleukin-17A (IL-17A) exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to produce...
Schlagworte: IL-17, IL17A, CTLA8, IL-17A, CTLA-8, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, Interleukin-17A,...
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~42 kD
391,00 €
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BMP-2 (human):Fc (human) (rec.) (non-lytic)
BMP-2 (human):Fc (human) (rec.) (non-lytic)

Artikelnummer: CHI-HF-220BMP2-C050

The extracellular domain of human BMP-2 (aa 289-396) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the BMP-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Bone...
Schlagworte: BMP2, BMP2A, BMP-2, BMP-2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
484,00 €
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CD274 [B7-H1/PD-L1] (mouse): Fc (mouse) (rec.)
CD274 [B7-H1/PD-L1] (mouse): Fc (mouse) (rec.)

Artikelnummer: CHI-MF-110PDL1-C100

Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
Schlagworte: B7h1, B7-H1, Cd274, PD-L1, CD274, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: mouse
418,00 €
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IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)
IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)

Artikelnummer: CHI-MF-12004-C010

The extracellular domain of mouse IL-4 (aa 21-140) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-4...
Schlagworte: Il4, IL-4, BSF-1, Interleukin-4, IGG1 induction factor, B-cell growth factor 1, B-cell stimulatory factor 1, Lymphocyte...
Anwendung: Bioassays
Exprimiert in: Mouse cells
Ursprungsart: mouse
ab 248,00 €
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FGF-21 (mouse) (rec.)
FGF-21 (mouse) (rec.)

Artikelnummer: CHI-MF-102FGF21-C050

Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has been identified as an important regulator of energy metabolism connecting nutrition, growth, reproduction and longevity. FGF-21 lacks the heparin-binding domain of most FGF proteins, allowing its secretion. FGF-21 is...
Schlagworte: Fgf21, FGF-21, Fibroblast growth factor 21
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: mouse
MW: ~23 kD
ab 226,00 €
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IL-7 (human) (rec.) (His)
IL-7 (human) (rec.) (His)

Artikelnummer: CHI-HF-20107-C050

Interleukin-7 (IL-7), is a hematopoietic growth factor and a member of the IL-7/IL-9 family. IL-7 stimulates the proliferation of lymphoid progenitors and is secreted by stromal cells in the bone marrow and thymus. IL-7 is also important for proliferation during certain stages of B cell maturation. IL-7 and the...
Schlagworte: IL7, IL-7, Interleukin-7, Interleukin-7, Lymphopoietin 1, LP-1
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~27 kD
ab 248,00 €
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CD252 [OX40L] (human) (rec.) (His)
CD252 [OX40L] (human) (rec.) (His)

Artikelnummer: CHI-HF-201CD252-C050

OX40L [CD252, TNFSF4] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic...
Schlagworte: CD252, Ox40l, OX40L, Tnfsf4, OX40 ligand, Tumor necrosis factor ligand superfamily member 4, TNFSF4
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~27 kD
391,00 €
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IL-6 (human):Fc (human) (rec.) MultiPack
IL-6 (human):Fc (human) (rec.) MultiPack

Artikelnummer: CHI-HF-21006-C050

The extracellular domain of human IL-6 (aa 30-212) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin 6 (IL-6) is a pleiotropic alphahelical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone...
Schlagworte: CDF, IL6, IL-6, BSF-2, IFNB2, IFN-beta-2, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation...
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
209,00 €
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IL-6R (human):Fc (human) (rec.)
IL-6R (human):Fc (human) (rec.)

Artikelnummer: CHI-HF-21006R-C050

The extracellular domain of human IL-6R (aa 20-359) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-6 (IL-6) is a multifunctional factor, which exerts its activities through binding to a highaffinity receptor complex consisting of two membrane...
Schlagworte: gp80, IL6R, CD126, IL-6RA, IL-6R 1, IL-6R-alpha, IL-6R subunit alpha, Membrane glycoprotein 80, IL-6 receptor subunit...
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
369,00 €
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CD160 (human):Fc (human) (rec.)
CD160 (human):Fc (human) (rec.)

Artikelnummer: CHI-HF-210CD160-C100

CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for...
Schlagworte: BY55, CD160, CD160 antigen, Natural killer cell receptor BY55, Natural Killer Cell Receptor BY55, NK28, NK1
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
429,00 €
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CD38 (human):Fc (human) (rec.)
CD38 (human):Fc (human) (rec.)

Artikelnummer: CHI-HF-210CD38-C100

CD38, also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling.CD38 is a multifunctional ectoenzyme that...
Schlagworte: T10, CD38, ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, cADPr hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1,...
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~70 kD
429,00 €
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CD279 [PD-1] (human):Fc (human) (rec.)
CD279 [PD-1] (human):Fc (human) (rec.)

Artikelnummer: CHI-HF-210PD1-C100

The extracellular domain of human CD279 [PD-1] (aa 25-167) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Programmed Death-1 (PD-1, CD279) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for...
Schlagworte: PD1, CD279, PDCD1, hPD-1, Protein PD-1, Programmed cell death protein 1
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
484,00 €
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