Produkte von Bethyl Laboratories

Bethyl

Auf der texanischen Ranch von Bethyl Laboratories Inc. in Montgomery, Texas, werden beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. In Zusammenarbeit mit namhaften Wissenschaftlerinnen und Wissenschaftlern identifiziert Bethyl kontinuierlich neue Targets, wodurch ein Antikörperprogramm entsteht, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl Laboratories sind einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler*innen sich auf Bethyl-Antikörper verlassen können. Seit 2021 ist Bethyl Laboratories Teil von FORTIS Life Sciences.

Mehr Informationen unter: www.fortislife.com und www.fortislife.com/bethyl-laboratories

Zu den Katalogen von Bethyl Laboratories

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Anti-SMC3
Anti-SMC3

Artikelnummer: A300-060A

Protein function: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to...
Schlagworte: Anti-BAM, Anti-hCAP, Anti-SMC3, Anti-SMC-3, Anti-Bamacan, Anti-SMC protein 3, Anti-Chromosome-associated polypeptide,...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-phospho-RNA Polymerase II (Ser2)
Anti-phospho-RNA Polymerase II (Ser2)

Artikelnummer: A300-654A

Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
Schlagworte: Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-TFEB
Anti-TFEB

Artikelnummer: A303-673A

Protein function: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a...
Schlagworte: Anti-TFEB, Anti-BHLHE35, Anti-bHLHe35, Anti-Transcription factor EB, Anti-Class E basic helix-loop-helix protein 35
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-SMC1
Anti-SMC1

Artikelnummer: A300-055A

Protein function: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can...
Schlagworte: Anti-SMC1A, Anti-Sb1.8, Anti-SMC-1A, Anti-DXS423E, Anti-SMC-1-alpha, Anti-SMC protein 1A, Anti-Structural maintenance of...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-p14ARF
Anti-p14ARF

Artikelnummer: A300-342A

Protein function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. [The UniProt Consortium]
Schlagworte: Anti-CDKN2, Anti-CDK4I, Anti-MTS-1, Anti-p16INK4A, Anti-p16-INK4, Anti-p16-INK4a, Anti-Multiple tumor suppressor 1,...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-GAPDH
Anti-GAPDH

Artikelnummer: A300-641A

Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the...
Schlagworte: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=1.2.1.12, EC=2.6.99.-, Anti-Peptidyl-cysteine S-nitrosylase GAPDH,...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-MOF/MYST1
Anti-MOF/MYST1

Artikelnummer: A300-992A

Protein function: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of...
Schlagworte: Anti-MOF, Anti-hMOF, Anti-KAT8, Anti-PP7073, Anti-MYST-1, Anti-Lysine acetyltransferase 8, Anti-Histone acetyltransferase...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-MafA (IHC)
Anti-MafA (IHC)

Artikelnummer: IHC-00352

Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved...
Schlagworte: Anti-Mafa, Anti-Transcription factor MafA, Anti-Pancreatic beta-cell-specific transcriptional activator, Anti-V-maf...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: mouse
ab 164,00 €
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Anti-53BP1
Anti-53BP1

Artikelnummer: A300-272A

Protein function: Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis (PubMed:12364621, PubMed:22553214, PubMed:23333306, PubMed:17190600, PubMed:21144835, PubMed:28241136). Plays a key role in the repair of...
Schlagworte: Anti-53BP1, Anti-p53BP1, Anti-p53-binding protein 1, Anti-TP53-binding protein 1
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-Matrin 3
Anti-Matrin 3

Artikelnummer: A300-591A

Protein function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. [The UniProt Consortium]
Schlagworte: Anti-MATR3, Anti-Matrin-3, Anti-KIAA0723
Anwendung: WB, IP, IHC, IHC-IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-53BP1 (IHC)
Anti-53BP1 (IHC)

Artikelnummer: IHC-00001

Protein function: Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis (PubMed:12364621, PubMed:22553214, PubMed:23333306, PubMed:17190600, PubMed:21144835, PubMed:28241136). Plays a key role in the repair of...
Schlagworte: Anti-53BP1, Anti-p53BP1, Anti-p53-binding protein 1, Anti-TP53-binding protein 1
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-MLL1
Anti-MLL1

Artikelnummer: A300-086A

Protein function: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the...
Schlagworte: Anti-ALL1, Anti-KMT2A, EC=2.1.1.43
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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