Produkte von Bethyl Laboratories

Bethyl

Auf der texanischen Ranch von Bethyl Labs werden beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. Bethyls Netzwerk mit namhaften Wissenschaftlern identifiziert fortlaufend neue Targets für die zellbiologische Forschung. Daraus entsteht ein Antikörperprogramm, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl Laboratories sind einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler sich auf Bethyl-Antikörper verlassen können.

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Anti-PDE3A
Anti-PDE3A

Artikelnummer: A302-740A

Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]
Schlagworte: Anti-PDE3A, Anti-CGI-PDE A, EC=3.1.4.17, Anti-Cyclic GMP-inhibited phosphodiesterase A, Anti-cGMP-inhibited 3',5'-cyclic...
Anwendung: WB, IP
Reaktivität: Human
ab 131,00 €
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Anti-phospho-RNA Polymerase II (Ser2)
Anti-phospho-RNA Polymerase II (Ser2)

Artikelnummer: A300-654A

Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
Schlagworte: Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-SMC1
Anti-SMC1

Artikelnummer: A300-055A

Protein function: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can...
Schlagworte: Anti-SMC1A, Anti-Sb1.8, Anti-SMC-1A, Anti-DXS423E, Anti-SMC-1-alpha, Anti-SMC protein 1A, Anti-Structural maintenance of...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-p14ARF
Anti-p14ARF

Artikelnummer: A300-342A

Protein function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. [The UniProt Consortium]
Schlagworte: Anti-CDKN2, Anti-CDK4I, Anti-MTS-1, Anti-p16INK4A, Anti-p16-INK4, Anti-p16-INK4a, Anti-Multiple tumor suppressor 1,...
Anwendung: WB, IHC
Reaktivität: Human
ab 131,00 €
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Anti-MOF/MYST1
Anti-MOF/MYST1

Artikelnummer: A300-992A

Protein function: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of...
Schlagworte: Anti-MOF, Anti-hMOF, Anti-KAT8, Anti-PP7073, Anti-MYST-1, Anti-Lysine acetyltransferase 8, Anti-Histone acetyltransferase...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-MafA (IHC)
Anti-MafA (IHC)

Artikelnummer: IHC-00352

Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved...
Schlagworte: Anti-Mafa, Anti-Transcription factor MafA, Anti-Pancreatic beta-cell-specific transcriptional activator, Anti-V-maf...
Anwendung: IHC
Reaktivität: Mouse
ab 131,00 €
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Anti-Matrin 3
Anti-Matrin 3

Artikelnummer: A300-591A

Protein function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. [The UniProt Consortium]
Schlagworte: Anti-MATR3, Anti-Matrin-3, Anti-KIAA0723
Anwendung: WB, IP, IHC, IHC-IF
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-GAPDH
Anti-GAPDH

Artikelnummer: A300-641A

Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the...
Schlagworte: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=1.2.1.12, EC=2.6.99.-, Anti-Peptidyl-cysteine S-nitrosylase GAPDH,...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-53BP1 (IHC)
Anti-53BP1 (IHC)

Artikelnummer: IHC-00001

Protein function: Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis (PubMed:12364621, PubMed:22553214, PubMed:23333306, PubMed:17190600, PubMed:21144835, PubMed:28241136). Plays a key role in the repair of...
Schlagworte: Anti-53BP1, Anti-p53BP1, Anti-p53-binding protein 1, Anti-TP53-binding protein 1
Anwendung: IHC
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-HdmX/MDM4
Anti-HdmX/MDM4

Artikelnummer: A300-287A

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt Consortium]
Schlagworte: Anti-MDM4, Anti-MDMX, Anti-Protein Mdm4, Anti-Protein Mdmx, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: WB, IP
Reaktivität: Human
ab 131,00 €
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Anti-CHD1
Anti-CHD1

Artikelnummer: A301-218A

Protein function: ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the...
Schlagworte: Anti-CHD1, Anti-CHD-1, EC=3.6.4.12, Anti-ATP-dependent helicase CHD1, Anti-Chromodomain-helicase-DNA-binding protein 1
Anwendung: WB, IP, ChIP, ChIP-chip, ChIP-Seq
Reaktivität: Human
ab 131,00 €
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Anti-BRD4
Anti-BRD4

Artikelnummer: A301-985A50

Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
Schlagworte: Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
493,00 €
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