Anti-IgG Heavy Chain, clone RM116

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R20177-100UG 100 µg - -

3 - 10 Werktage*

737,00 €
 
1 mg/ml in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This recombinant Human IgG... mehr
Produktinformationen "Anti-IgG Heavy Chain, clone RM116"
1 mg/ml in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This recombinant Human IgG antibody reacts to the Fc region of all gamma heavy chains of human immunoglobulins, including G1, G2, G3, and G4. No cross reactivity with other human heavy chains or mouse/rat/goat IgG. Protein function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins- secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Mediates IgG effector functions on monocytes triggering ADCC of virus- infected cells. [The UniProt Consortium]
Schlagworte: Anti-Ig gamma-1 chain C region, Anti-Ig gamma-1 chain C region EU, Anti-Ig gamma-1 chain C region KOL, Anti-Ig gamma-1 chain C region NIE, Anti-Immunoglobulin heavy constant gamma 1, IgG Heavy Chain Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R20177

Eigenschaften

Anwendung: ICC, IHC, ELISA
Antikörper-Typ: Monoclonal
Klon: RM116
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Human IgG
Format: Purified

Datenbank Information

UniProt ID : P01857 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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