Anti-Estrogen receptor beta (B region)

There are two classes of Estrogen Receptors (ER,) the first is intracellular and translocate to the Nucleus when activated through binding to 17 beta estradiol. They are named ER alpha and ER beta. The second G protein couples receptors which are membranes proteins and have intracellular signaling function. central ERa signaling is necessary for the actions of GLP-1 on food-reward behavior.