Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Nampt (Visfatin/PBEF) (human) ELISA Kit
Artikelnummer: AG-45A-0006YEK-KI01
Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form...
| Schlagworte: | PBEF, NAMPT, Nampt, Visfatin, NAmPRTase, EC=2.4.2.12, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 682,00 €
SB203580
Artikelnummer: AG-CR1-0030-M001
Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferative, PDK1 inhibitor, Anti-inflammatory, Review.
| Schlagworte: | 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole |
| Anwendung: | p38 MAP kinase inhibitor |
| CAS | 152121-47-6 |
| MW: | 377,4 D |
ab 39,00 €
MG-132
Artikelnummer: AG-CP3-0011-M005
Soluble in DMSO or ethanol. Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kappaB activation inhibitor through IkappaB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin...
| Schlagworte: | Z-Leu-Leu-Leu-CHO, Z-LLL-CHO, Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, MG132 |
| Anwendung: | Proteasome inhibitor |
| CAS | 133407-82-6 |
| MW: | 476 D |
ab 22,00 €
Anti-ADAM17 (human) (blocking), clone D1(A12)
Artikelnummer: AG-27B-6000PF-C100
Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor...
| Schlagworte: | Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
| Anwendung: | FA (blocking) |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
572,00 €
Paclitaxel
Artikelnummer: AG-CN2-0045-M005
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
| Schlagworte: | Taxol, BMS 181339-01, NSC 125973 |
| Anwendung: | Apoptosis Inducer |
| Wirt: | Taxus brevifolia |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
ab 22,00 €
Progranulin (human) (rec.) (untagged)
Artikelnummer: AG-40A-0188Y-C050
Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
| Schlagworte: | GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Anwendung: | Cell culture |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 74 kD |
ab 215,00 €
Progranulin (human) ELISA Kit
Artikelnummer: AG-45A-0018YEK-KI01
Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Culture Supernatant , Plasma , Serum. Sensitivity: 32pg/ml. Range: 0.063 to 4ng/ml. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating...
| Schlagworte: | Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 649,00 €
Latrunculin B
Artikelnummer: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Schlagworte: | LAT-B, NSC 339663 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
ab 143,00 €
Anti-Caspase-1 (p10) (mouse), clone Casper-2
Artikelnummer: AG-20B-0044-C100
Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4...
| Schlagworte: | Interleukin-1 beta Convertase, IL-1BC, Interleukin-1 beta-converting Enzyme, ICE |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
440,00 €
![Anti-Polyglutamate chain [Poly-E]](https://www.biomol.com/media/image/e5/f7/cf/AG-25B-0030-C050_200x200.png "Anti-Polyglutamate chain [Poly-E]")
Anti-Polyglutamate chain [Poly-E]
Artikelnummer: AG-25B-0030-C050
Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and...
| Schlagworte: | Anti-Poly-E, pAb (IN105), Anti-Poly-Glu |
| Anwendung: | WB, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | broad |
429,00 €
Thapsigargin (high purity)
Artikelnummer: AG-CN2-0003-M001
Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
| Anwendung: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650,8 D |
ab 77,00 €
Rapamycin
Artikelnummer: AG-CN2-0025-M001
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
| Schlagworte: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Anwendung: | mTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| CAS | 53123-88-9 |
| MW: | 914,2 D |
ab 28,00 €