Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Insulin (human) ELISA Kit
Artikelnummer: AG-45B-0031-KI01
Glucose is the main fuel for the human body and blood glucose values are tightly regulated in healthy individuals. Regulation of glucose uptake in cells is performed by the hormone called insulin which is glucose-responsively secreted from pancreatic beta cells. When the glucose concentration in the blood is...
| Schlagworte: | INS, Insulin A Chain & Insulin B Chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
528,00 €
Isthmin-1 (human) ELISA Kit
Artikelnummer: AG-45B-0032-KI01
Isthmin-1 (ISM1) was first identified as a gene expressed in the Xenopus midbrain-hindbrain organizer called the isthmus, with a proposed role during early brain development. Isthmin-1 encodes a predicted ~50-kDa protein containing a signal peptide, a thrombospondin domain and an adhesion-associated domain....
| Schlagworte: | ISM1, C20orf82, Isthmin-1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
561,00 €
BAFF, Soluble (mouse) ELISA Kit
Artikelnummer: AG-45B-0033-KI01
BAFF (B cell-activating factor, BLyS, B lymphocyte stimulator, TNFSF13B, TALL-1, CD257), belonging to the TNF family, is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. BAFF levels are...
| Schlagworte: | Baff, Tnfsf13b, BlyS, B Cell Activating Factor, CD257, Tumor necrosis factor ligand superfamily member 13B, TNFSF13B |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
660,00 €
Latrunculin A
Artikelnummer: AG-CN2-0027-C100
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in...
| Schlagworte: | LAT-A, NSC 613011 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-93-6 |
| MW: | 421,6 D |
ab 143,00 €
Cyclosporin A (5x100mg)
Artikelnummer: AG-CN2-0079-M100
Potent immunosuppressant (same as FK-506 (Prod. No. AG-CN2-0047) and rapamycin (Prod. No. AG-CN2-0025)) - Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B, calcineurin). Prevents the dephosphorylation of nuclear factor of activated T cells...
| Schlagworte: | Antibiotic S 7481F1, Ciclosporin A, CsA, Cyclosporine, NSC 290193, Ramihyphin A |
| Anwendung: | Immunsuppressant |
| CAS | 59865-13-3 |
| MW: | 1202,6 D |
ab 55,00 €
MCC950 . Na
Artikelnummer: AG-CR1-3615-M001
Crystalline solid. Soluble in water (10mg/ml), DMSO (10mg/ml), dimethyl formamide or ethanol (1mg/ml). Chemical. CAS: 256373-96-3. Formula: C20H23N2NaO5S. MW: 426.5. Synthetic. Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and...
| Schlagworte: | MCC950, CP-456,773, CRID3, 1-(1,2,3,5,6,7-Hexahydro- s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea |
| Anwendung: | NLRP3 inflammasome inhibitor |
| CAS | 256373-96-3 |
| MW: | 426,5 D |
ab 39,00 €
IL-33 (oxidation resistant) (human) (rec.) (untagged)
Artikelnummer: AG-40B-0160-C100
Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4 and TRAF6, followed...
| Schlagworte: | IL33, C9orf26, IL-33 (human) (C208S/C232S), Interleukin-33 (human) (C208S/C232S), IL-1F11, NF-HEV |
| Anwendung: | Cell culture, binding assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 17 kD |
ab 286,00 €
Actinomycin D
Artikelnummer: BVT-0089-M005
Antibiotic, Antitumor compound, Cytotoxic, Apoptosis inducer, RNA synthesis inhibitor, DNA intercalating agent, Mcl-1 expression inhibitor, p53 pathway activator. Isolated from Streptomyces parvulus.
| Schlagworte: | Actinomycin IV, Actinomycin C1, Dactinomycin |
| Anwendung: | p53 pathway activator |
| CAS | 50-76-0 |
| MW: | 1255,4 D |
ab 55,00 €
Arginase I (human) (rec.) (highly active)
Artikelnummer: AG-40T-0124-C010
Protein function: Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver...
| Schlagworte: | ARG1, Arginase-1, Type I arginase, Liver-type arginase |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
ab 286,00 €
Gasdermin D (mouse) ELISA Kit
Artikelnummer: AG-45B-0011-KI01
Detects full-length and cleaved mouse Gasdermin D (C-terminus) in cell culture supernatants and cell extracts. Does not cross-react with human gasdermin D. Sensitivity: 14pg/ml. Range: 15.6 to 1000pg/ml. Protein function: Gasdermin-D, N-terminal: Promotes pyroptosis in response to microbial infection and danger...
| Schlagworte: | Gsdmd, Gsdmdc1, Gasdermin Domain-containing Protein 1, Gasdermin-D (C-terminal), GSDMD-CT |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
660,00 €
Flagellin (high purity)
Artikelnummer: AG-40B-0025-3010
(3 x 10µg). Activation of TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, on expression of IL-8 (CXCL8), CCL20, inducible nitric oxide synthase, beta-defensin 2 and matrilysin (MMP-7). Maturation of dendritic cells in in vitro and in vivo assays. Adjuvant activity on foreign antigens...
| Schlagworte: | FliC |
| Anwendung: | Bioassays |
| Ursprungsart: | human, mouse |
ab 198,00 €
(-)-Viriditoxin
Artikelnummer: AG-CN2-0471-C500
Solid. Soluble in DMSO or ethanol. Antibiotic. Exhibits broad activity against Gram-positive bacteria, Bacterial cell division protein FtsZ inhibitor (IC50=8.2µg/ml). Inhibits the GTPase activity of FtsZ in vitro (IC50=7.0µg/ml), Induces apoptosis and autophagy and inhibits cell growth at G2/M in human prostate...
| Schlagworte: | (M)-Viriditoxin, SC-28762 |
| Anwendung: | Antibiotic (Gram-positive bacteria), FtsZ inhibitor |
| CAS | 1381782-08-6 |
| MW: | 662,6 D |
154,00 €