Products from Cayman

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

2 from 1081 pages
No results were found for the filter!
10-Nitrolinoleate
10-Nitrolinoleate

Item number: Cay10037-100

10-Nitrolinoleate is the product of nitration of linoleate by NO-derived reactive species. Other nitrolinoleates detected in human plasma and urine include 9-, 12-, and 13-nitrolinoleate. Nitrolinoleates activate peroxisome proliferator-activated receptor gamma (PPARgamma, Ki = 133 nM), inducing CD36 expression in macrophages, adipocyte differentiation, and glucose uptake....
Application: PPAR gamma activator
CAS 774603-04-2
MW: 325.4 D
Purity: >95%
Format: Solution
From 48.00€
Review
Prostaglandin E2-d9
Prostaglandin E2-d9

Item number: Cay10581-250

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences...
Application: Standard
CAS 1356347-42-6
MW: 361.5 D
Purity: >99% deuterated forms (d1-d9)
Format: Solution
From 64.00€
Review
BAPTA
BAPTA

Item number: Cay11706-100

BAPTA is a membrane-impermeable calcium chelator that binds extracellular calcium ions. The presence of four carboxylic acid functional groups allows for the binding of two calcium ions. BAPTA and its derivatives are widely used for the measurement and manipulation of intracellular free calcium concentration.
Application: Calcium chelator
CAS 85233-19-8
MW: 476.4 D
Purity: >95%
Format: Crystalline Solid
From 32.00€
Review
SAG
SAG

Item number: Cay11914-5

Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors. Smoothened agonist (SAG) is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 µM). It directly binds to SMO and can block SMO...
Application: Smo Agonist
CAS 912545-86-9
MW: 490.1 D
Purity: >98%
Format: Crystalline Solid
From 110.00€
Review
Streptozotocin
Streptozotocin

Item number: Cay13104-500

Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and ATP, and formation of superoxide radicals, leading to the...
Application: Diabetes inducer, NO donor
CAS 18883-66-4
MW: 265.2 D
Purity: >95%
Format: Crystalline Solid
From 32.00€
Review
Oleoyl Serinol
Oleoyl Serinol

Item number: Cay13637-100

Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine neuroblastoma and apoptosis in U-87 human astrocytoma cells...
Application: GPR119 agonist
CAS 72809-08-6
MW: 355.6 D
Purity: >98%
Format: Crystalline Solid
From 42.00€
Review
Bromocriptine (mesylate)
Bromocriptine (mesylate)

Item number: Cay14598-100

Bromocriptine is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM). As a result, it has found applications in combination therapy for Parkinsonism. Bromocriptine also avidly binds the serotonin receptors 5-HT1A and 5-HT1D (Ki = 12.9 and 10.7 nM, respectively), as well as alpha and beta adrenoreceptors. It also inhibits neuronal...
Application: Dopamine D2 receptor agonist
CAS 22260-51-1
MW: 750.7 D
Purity: >98%
Format: Crystalline Solid
From 44.00€
Review
Cathepsin G Inhibitor I
Cathepsin G Inhibitor I

Item number: Cay14928-1

Cathepsin G inhibitor I is a potent and selective inhibitor of cathepsin G (IC50 = 53 nM). It weakly inhibits or has no effect on related proteases, including chymotrypsin, thrombin, plasmin, trypsin, tryptase, and elastase.
Application: Cathepsin G inhibitor
CAS 429676-93-7
MW: 620.6 D
Purity: >95%
Format: Crystalline Solid
From 49.00€
Review
N-Acetylneuraminic Acid
N-Acetylneuraminic Acid

Item number: Cay16091-100

Salic acids are nine-carbon carbohydrate alpha-keto acids that have many important biological functions, including cell-cell recognition and host-pathogen interactions. N-Acetylneuraminic acid (NANA) is the most abundant sialic acid and is found in bacteria as well as in eukaryotic cells. The pathways for NANA synthesis and metabolism in bacteria differ from those used in...
Application: Sialic acid
CAS 131-48-6
MW: 309.3 D
Purity: >98%
Format: Crystalline Solid
From 32.00€
Review
Guanylyl Imidodiphosphate
Guanylyl Imidodiphosphate

Item number: Cay16880-25

Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+. This nucleotide is a potent stimulator of adenylate cyclase. Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and release is essential for the initiation of protein...
Application: Nonhydrolyzable GTP analog
CAS 148892-91-5
MW: 588.1 D
Purity: >95%
Format: Crystalline Solid
From 44.00€
Review
WYE-125132
WYE-125132

Item number: Cay18372-1

The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin (Cay-13346)) and regulate different pathways. WYE-125132 is an ATP-competitive inhibitor of mTOR (IC50 = 0.19 nM) that inhibits signaling through both...
Application: MTOR inhibitor
CAS 1144068-46-1
MW: 519.6 D
Purity: >98%
Format: Crystalline Solid
From 37.00€
Review
Hexaflumuron
Hexaflumuron

Item number: Cay18598-250

Hexaflumuron is a chitin synthesis inhibitor used to bait and eliminate termite colonies. Hexaflumuron spreads efficiently through entire populations through mutual exchange of liquids via regurgitation. Termites are unable to metabolize hexaflumuron and clearance is slow, resulting in up to 100% elimination. Hexaflumuron has also been tested for use with the raisin moth,...
Application: Chitin synthesis inhibitor
CAS 86479-06-3
MW: 461.1 D
Purity: >95%
Format: Crystalline Solid
From 63.00€
Review
2 from 1081 pages
Viewed