Products from Cayman

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

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Nepsilon-(1-Carboxymethyl)-L-lysine-d3
Nepsilon-(1-Carboxymethyl)-L-lysine-d3

Item number: Cay26785-500

Nepsilon-(1-Carboxymethyl)-L-lysine-d3 (CML-d3) is intended for use as an internal standard for the quantification of CML (Cay-16483) by GC- or LC-MS. CML is an advanced glycation end product (AGE), produced by the oxidative modification of glycated proteins during oxidative stress. Levels of CML increase with aging and during diabetes, cancer, vascular disease, and other...
Application: GC-MS, LC-MS, Quantification, Internal standard, Advanced glycation endproduct (AGE), AGER/RAGE ligand
MW: 207.2 D
Purity: >99% deuterated forms (d1-d3)
Format: Solid
From 187.00€
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Hydroxystilbamidine (methanesulfonate)
Hydroxystilbamidine (methanesulfonate)

Item number: Cay26858-5

Hydroxystilbamidine is a fluorescent neuronal retrograde tracer that labels the neuronal cell body as well as proximal dendrites. Hydroxystilbamidine, when visualized in tissue sections, displays excitation/emission maxima of 323/620 nm, respectively. It is also a nucleic acid dye that can be used to label DNA and RNA in fixed or unfixed dead cells. It displays an excitation...
Application: Fluorescent neuronal retrograde tracer
CAS 223769-64-0
MW: 472.5 D
Format: Solid
From 105.00€
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ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
ACTH (1-10) (human, mouse, rat, porcine,...

Item number: Cay27105-5

Adrenocorticotropic hormone (ACTH) (1-10) is an N-terminal peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. The amino acid sequence of ACTH (1-10) is common to ACTH and alpha-melanocyte stimulating hormone. ACTH (1-10) is an agonist of melanocortin receptor 3 (MC3R) and MC4R (EC50s = 2.6...
Application: MC3R / MC4R agonist
MW: 1299.4 D
Purity: >95%
Format: Solid
From 62.00€
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Ac-VEID-pNA (trifluoroacetate salt)
Ac-VEID-pNA (trifluoroacetate salt)

Item number: Cay27104-5

Ac-VEID-pNA is a substrate for caspase-6. Caspase-6 binds to and cleaves the Val-Glu-Ile-Asp (VEID) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.
Application: Caspase-6 substrate
MW: 636.7 D
Purity: >95%
Format: Solid
From 32.00€
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PPARgamma-LBD Ligand Screening Assay Kit
PPARgamma-LBD Ligand Screening Assay Kit

Item number: Cay600616-384

Cayman's PPARgamma-LBD Ligand Screening Assay Kit provides a convenient fluorescence polarization (FP)-based single-step assay for screening ligands of the PPARgamma-Ligand Binding Domain (PPARgamma-LBD). In this assay, a ligand of PPARgamma is conjugated to fluorescein and is used as the displacement probe. Ligands, agonist, and antagonists of PPARgamma-LBD will displace...
Application: Binding Assay
Format: Homog.
619.00€
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Stem Cell Small Molecule Screening Library (96-Well)
Stem Cell Small Molecule Screening Library...

Item number: Cay9001827-50

The Stem Cell Small Molecule Screening Library contains more than 140 small molecules that are known either to induce differentiation, to maintain self-renewal and proliferation, or to improve the reprogramming efficiency of various stem cell populations. These compounds are supplied in a 96-well Matrix tube rack format as 10 mM stocks in DMSO. The composition of this...
Application: Compound screening
Format: Solution
2,469.00€
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D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt)
D-myo-Inositol-1,2,3,4,5,6-hexaphosphate...

Item number: Cay10008415-50

D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (IP6) is a phosphate ester of inositol. It is found in mammalian cells and undergoes interconversion to other forms of inositol phosphate that act as second messengers in cell signaling. IP6 is an antioxidant that chelates iron at a molar ratio of 1:4 to reduce iron-induced hydroxy radical production and lipid peroxidation in...
Application: Iron-induced hydroxy radical production / lipid peroxidation inhibitor
CAS 34367-89-0
MW: 791.9 D
Purity: >98%
Format: Solid
From 119.00€
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(±)19(20)-DiHDTE
(±)19(20)-DiHDTE

Item number: Cay20336-50

(±)19(20)-DiHDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid (DPA, Cay-21907). It is formed via cytochrome P450 (CYP) metabolism of DPA via a (±)19(20)-EpDTE (Cay-20331) intermediate.
Application: Oxylipin
MW: 364.5 D
Purity: >98%
Format: Solution
From 95.00€
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2,6-Dibromoquinone-4-chloroimide
2,6-Dibromoquinone-4-chloroimide

Item number: Cay21056-5

2,6-Dibromoquinone-4-chloroimide is a colorimetric dye for the detection of phenolic compounds. It produces an indigo dye upon reacting with phenolic compounds at a pH of approximately 9.4. 2,6-Dibromoquinone-4-chloroimide has been used as a Gibbs reagent for the colorimetric detection of phenolic compounds. It has also been used in chromogenic reactions for the quantitative...
Application: Colorimetric dye, Phenolic compound detection, Quantitative colorimetric aflatoxin detection
CAS 537-45-1
MW: 299.3 D
Purity: >95%
Format: Crystalline Solid
From 34.00€
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IRL 2500
IRL 2500

Item number: Cay23363-5

Application: Endothelin receptor type B (ETBR) antagonist
CAS 169545-27-1
MW: 573.7 D
From 182.00€
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PD 151746
PD 151746

Item number: Cay23417-50

PD 151746 is an inhibitor of calpain 1/µ-calpain (Ki = 0.26 µM). It is 20-fold selective for calpain 1 over calpain 2/m-calpain (Ki = 5.33 µM). It is also selective over cathepsin B, papain, trypsin, and thermolysin, (Kis = >200, >500, >500, and >500 µM, respectively) and does not inhibit basal calcineurin activity (Ki = >200 µM) but does inhibit calmodulin-induced...
Application: Calpain-1 inhibitor
CAS 179461-52-0
MW: 237.2 D
Purity: >98%
Format: Crystalline Solid
From 75.00€
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Beclin 1 (human recombinant)
Beclin 1 (human recombinant)

Item number: Cay24495-100

Beclin 1 (BECN1) is a core component of the class III phosphatidylinositol 3-kinase (PI3K) complex, which generates phosphatidylinositol 3-phosphate (PI3P) and has functions in macroautophagy and the endocytic pathway when associated with ATG14 and UVRAG, respectively. BECN1 is comprised of a BH3 domain involved in Bcl-2/Bcl-xL binding, a coiled-coil domain, and an...
Application: WB control
MW: 53.9 kD
Purity: >80% estimated by SDS-PAGE
494.00€
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