Products from Cayman

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

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Corticosterone ELISA Kit
Corticosterone ELISA Kit

Item number: Cay501320-96

Corticosterone is a glucocorticoid produced by the adrenal cortex in response to ACTH (corticotropic hormone) and is the precursor to aldosterone. The production of glucorcorticoids is increased by stress, therefore, corticosterone can be used as a biomarker of stress. Biologists often measure corticosterone in...
Keywords: 11beta,21-DHP, 11beta,21-dihydroxy Progesterone, 17-deoxy Cortisol, Corticosterone EIA Kit
Application: ELISA
From 307.00€
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Superoxide Dismutase Assay Kit
Superoxide Dismutase Assay Kit

Item number: Cay706002-480

Significant amounts of superoxide dismutase (SOD) in cellular and extracellular environments are crucial for the prevention of diseases linked to oxidative stress. Mutations in SOD account for approximately 20% of familial amyotrophic lateral sclerosis (ALS) cases. SOD also appears to be important in the prevention...
Keywords: SOD
Application: SOD detection
From 282.00€
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Mifepristone
Mifepristone

Item number: Cay10006317-5

Mifepristone is an antagonist of glucocorticoid, progesterone, and androgen receptors (Kis = 0.1, 0.64, and 0.65 nM, respectively). It is selective for these receptors over the mineralocorticoid receptor (MR), estrogen receptor alpha (ERalpha), and ERbeta (Kis = 640, >200, and >750 nM, respectively). In cell-based...
Keywords: RU-486, 11beta-[4-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one
Application: PR antagonist, GR antagonist
CAS 84371-65-3
MW: 429.6 D
From 32.00€
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Prostaglandin E2-d9
Prostaglandin E2-d9

Item number: Cay10581-250

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Keywords: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Application: Standard
CAS 1356347-42-6
MW: 361.5 D
From 64.00€
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BAPTA
BAPTA

Item number: Cay11706-100

BAPTA is a membrane-impermeable calcium chelator that binds extracellular calcium ions. The presence of four carboxylic acid functional groups allows for the binding of two calcium ions. BAPTA and its derivatives are widely used for the measurement and manipulation of intracellular free calcium concentration.
Keywords: N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-glycine
Application: Calcium chelator
CAS 85233-19-8
MW: 476.4 D
From 32.00€
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Oleoyl Serinol
Oleoyl Serinol

Item number: Cay13637-100

Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
Keywords: N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide
Application: GPR119 agonist
CAS 72809-08-6
MW: 355.6 D
From 42.00€
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D-(-)-3-Phosphoglyceric Acid (sodium salt)
D-(-)-3-Phosphoglyceric Acid (sodium salt)

Item number: Cay20123-10

D-(-)-3-Phosphoglyceric acid is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine. It also has numerous roles as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.
Keywords: 2R-hydroxy-3-(phosphonooxy)-propanoic acid, disodium salt
Application: Glycolysis intermediate, Serine precursor
CAS 80731-10-8
MW: 230 D
From 19.00€
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Pirlimycin
Pirlimycin

Item number: Cay20138-1

Pirlimycin is a lincosamide antibiotic that is effective against Gram-positive bacteria, including Staphylococcus, Streptococcus, Bacteroides, and Plasmodium. It inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome. Pirlimycin has been used by veterinarians in the treatment of mastitis...
Keywords: U-57930E, methyl...
Application: Antibacterial, Lincosamide antibiotic, Protein biosynthesis inhibitor
CAS 79548-73-5
MW: 411 D
From 240.00€
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Epibrassinolide
Epibrassinolide

Item number: Cay20337-1

Epibrassinolide is a brassinosteroid that can be isolated from various plants and has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress. Epibrassinolide is also reported to be a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. It...
Keywords: 24-Epibrassinolide, EBL,...
Application: Brassinosteroid, Apoptotic inducer
CAS 78821-43-9
MW: 480.7 D
From 69.00€
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Acolbifene
Acolbifene

Item number: Cay23931-1

Acolbifene is a selective estrogen receptor modulator (SERM). It inhibits transcriptional activity of estrogen receptor alpha (ERalpha) and ERbeta induced by estradiol (E2, Cay-10006315, IC50s = 2 and 0.4 nM, respectively). It binds to ERs in cytosol from human breast cancer and non-cancerous uterine cells (Kis =...
Keywords: EM-652, SCH 57068, (2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol
Application: Selective estrogen receptor modulator (SERM
CAS 182167-02-8
MW: 457.6 D
From 75.00€
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DuP-697
DuP-697

Item number: Cay70645-5

DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2. When tested on isolated recombinant enzymes, DuP-697 is at least 50 times more potent in the inhibition of COX-2...
Keywords: 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene
Application: COX-2 inhibitor
CAS 88149-94-4
MW: 411.3 D
From 112.00€
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15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide
15(R)-17-phenyl trinor Prostaglandin F2alpha...

Item number: Cay10008127-10

15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide (15(R)-17-phenyl trinor PGF2alpha ethyl amide) is an isomer of bimatoprost, characterized by an inverted (beta) hydroxyl group at C-15. While this isomer has not been characterized, the comparable inversion of 15-hydroxyl groups, from (S) to (R), on other...
Keywords: 15(R)-17-phenyl trinor PGF2alpha ethyl amide, 15(R)-Bimatoprost,...
Application: Bioactive lipid assays
CAS 1163135-92-9
MW: 415.6 D
From 80.00€
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