Products from Cayman Chemical

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

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Uric Acid (sodium salt)
Uric Acid (sodium salt)

Item number: Cay16219-2

Uric acid is a ubiquitous end product of purine metabolism in humans that is mainly excreted in urine, whereas in other mammals it is further metabolized to allantoin by uricase. The final two steps in its production are catalyzed by xanthine oxidase, which generates superoxide. Uric acid acts as a potent...
Keywords: 7,9-dihydro-1H-purine-2,6,8(3H)-trione, monosodium salt
Application: Antioxidant, Disease causing agent
CAS 1198-77-2
MW: 190.1 D
87.00€
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Helenalin
Helenalin

Item number: Cay17050-1

Helenalin is a sesquiterpene lactone first isolated from various species of Arnica. It has anti-inflammatory effects, most notably by inhibiting gene expression mediated by NF-kappaB at doses from 1 to 20 µM. Like other sesquiterpene lactones, helenalin can modify sulfhydryl groups of cysteine residues and it...
Keywords: NSC 85236, 3,3aS,4S,4aR,7aR,8R,9,9aR-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-azuleno[6,5-b]furan-2,5-dione
Application: Antiinflammatory, NF-kappaB mediated gene expression inhibitor
CAS 6754-13-8
MW: 262.3 D
519.00€
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CytoTrace(TM) Orange CMTMR
CytoTrace(TM) Orange CMTMR

Item number: Cay20696-50

CytoTrace(TM) Orange CMTMR is a rhodamine-based, cell-permeant, vital fluorescent dye that is retained by cells for prolonged periods (>72 hours) and is passed to daughter cells. Cells loaded with long-lasting dyes, including CMTMR, are used to follow cell trafficking and cell-to-cell interactions in vivo. They have...
Keywords: CellTracker(TM) Orange CMTMR, 9-[2-carboxy-4(or...
Application: FC, Fluorescence
CAS 323192-14-9
MW: 554 D
57.00€
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Cyclic AMP ELISA Kit
Cyclic AMP ELISA Kit

Item number: Cay581001-96

Cayman's cAMP assay is a very sensitive competitive ELISA that permits cAMP measurements within the standard curve range of 0.078-10 pmol/ml, typically with a sensitivity (80% B/B0) of 0.1 pmol/ml once samples and standards have been acetylated prior to analysis. This assay has been validated with culture media,...
Keywords: Adenosine 3',5'-cyclic mononucleotide, Adenosine 3',5'-cyclic monophosphate, cAMP EIA Kit
Application: ELISA
From 338.00€
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Testosterone ELISA Kit
Testosterone ELISA Kit

Item number: Cay582701-96

Testosterone is the prototypic and predominant circulating androgenic steroid. It plays a major role in the growth and function of many reproductive and non-reproductive tissues and organs including muscle, liver, and brain, directing the development of the male phenotype during embryogenesis and at puberty....
Keywords: Testosterone EIA Kit
Application: ELISA
From 288.00€
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TNF-alpha (human) ELISA Kit
TNF-alpha (human) ELISA Kit

Item number: Cay589201-96

Tumor Necrosis Factor-alpha (TNF-alpha) is a 17 kDa polypeptide produced primarily by activated monocytes and macrophages. This polypeptide mediates many immune and inflammatory responses, including activation and differentiation of monocytes and macrophages, expression of MHC class I and II, and expression of...
Keywords: TNF, TNFA, TNF-a, Cachectin, TNF-alpha, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2
Application: ELISA
Reactivity: Human
From 454.00€
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Antioxidant Assay Kit
Antioxidant Assay Kit

Item number: Cay709001-96

The antioxidant system of living organisms includes enzymes such as superoxide dismutase, catalase, and glutathione peroxidase, macromolecules such as albumin, ceruloplasmin, and ferritin, and an array of small molecules, including ascorbic acid, alpha-tocopherol, beta-carotene, reduced glutathione, uric acid, and...
Application: Antioxidant capacity determination
288.00€
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PAF Acetylhydrolase Assay Kit
PAF Acetylhydrolase Assay Kit

Item number: Cay760901-96

Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of cells upon stimulation. PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Plasma PAF-AH is highly selective for phospholipids with very short acyl groups at the sn-2...
Keywords: PAFAH, PLA2G7, gVIIA-PLA2, LDL-PLA(2), EC=3.1.1.47, PAF 2-acylhydrolase, PAF acetylhydrolase, Group-VIIA phospholipase A2,...
Application: PAF Acetylhydrolase activity detection
Reactivity: Human
262.00€
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Arachidic Acid
Arachidic Acid

Item number: Cay9000339-100

Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi. It inhibits rabbit neutrophil aggregation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP, Cay-21495) when used at a concentration of 5 µM. Formulations containing arachidic acid have been used as...
Keywords: n-Eicosanoic Acid, Arachic Acid, C20:0, Icosanoic Acid, NSC 93983, eicosanoic acid
Application: Bioactive lipid assays
CAS 506-30-9
MW: 312.5 D
From 13.00€
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Prostaglandin E2-d9
Prostaglandin E2-d9

Item number: Cay10581-250

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Keywords: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Application: Standard
CAS 1356347-42-6
MW: 361.5 D
From 64.00€
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BAPTA
BAPTA

Item number: Cay11706-100

BAPTA is a membrane-impermeable calcium chelator that binds extracellular calcium ions. The presence of four carboxylic acid functional groups allows for the binding of two calcium ions. BAPTA and its derivatives are widely used for the measurement and manipulation of intracellular free calcium concentration.
Keywords: N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-glycine
Application: Calcium chelator
CAS 85233-19-8
MW: 476.4 D
From 32.00€
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SAG
SAG

Item number: Cay11914-1

Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors. Smoothened agonist (SAG) is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high...
Keywords: Smoothened Agonist,...
Application: Smo Agonist
CAS 912545-86-9
MW: 490.1 D
From 110.00€
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