Products from BPS Bioscience
Sun, sea, and science: BPS Bioscience from San Diego, California promotes new scientific discoveries that lead to therapies by creating innovative solutions for research. BPS is an expert in recombinant proteins and enzymes, cell lines, virus-based tools, as well as biochemical and cellular assay systems. The high-quality products and services from BPS enable researchers worldwide to advance biological discoveries in a variety of disciplines, including epigenetics, cell signaling, SARS-CoV-2, immunotherapy, CRISPR, and adoptive cell therapies.
More information at: www.bpsbioscience.com
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MMAE
Item number: BPS-82273-1
MMAE is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself, instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. Monomethyl auristatin E or MMAE is 100-1000 times more potent than doxorubicin. It is a very potent antimitotic agent that...
| Keywords: | Monomethyl auristatin E, |
| Application: | ADC payload, tubulin polymerization inhibitor, very potent antimitotic agent, cell division inhibitor |
| MW: | 718,0 D |
From 763.00€
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Val-Cit-PAB-MMAE
Item number: BPS-82274-1
Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate. It contains a a protease-sensitive Val-Cit dipeptide, and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells.
| Application: | ADC payload, synthetic antineoplastic agent |
| MW: | 1123,5 D |
From 1,448.00€
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MC-Val-Cit-PAB-MMAE
Item number: BPS-82275-1
MC-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate. It contains a thio reactive maleimidocaproyl (MC) group, a protease-sensitive Val-Cit dipeptide, a PABC linker and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward...
| Application: | ADC payload, synthetic antineoplastic agent |
| MW: | 1316,7 D |
From 656.00€
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Acid-PEG4-Val-Cit-PAB-MMAE
Item number: BPS-82276-1
Acid-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker featuring a carboxylic acid, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide ligated to an MMAE payload. Carboxylic acids are reactive towards amines or alcohols while the Val-Cit-PAB motif is an enzyme-cleavable linker. This linker efficiently releases the...
| Application: | ADC payload, cleavable amine-reactive ADC linker, apoptosis inducer |
| MW: | 1399,7 D |
From 943.00€
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Azide-PEG8-Val-Cit-PAB-MMAE
Item number: BPS-82277-1
Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a Val-Cit dipeptide, a PAB group, and an MMAE warhead. The azide is free to participate in click chemistry with terminal alkynes or strained cyclooctynes such as DBCO or BCN. The Val-Cit dipeptide is cleaved by cellular...
| Application: | ADC payload, click chemistry, cleavable alkyne-reactive ADC linker, apoptosis inducer |
| MW: | 1573,0 D |
From 975.00€
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Chemi-Verse(TM) GSK3alpha Kinase Assay Kit
Item number: BPS-82566
The Chemi-Verse(TM) GSK3alpha Kinase Assay Kit is designed to measure GSK3alpha (Glycogen Synthase Kinase 3 Alpha) serine/threonine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified GSK3alpha,...
| Keywords: | GSK3A, GSK-3 alpha, EC=2.7.11.26, Glycogen synthase kinase-3 alpha, Serine/threonine-protein kinase GSK3A, |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
827.00€
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Chemi-Verse(TM) GSK3beta Kinase Assay Kit
Item number: BPS-82567
The Chemi-Verse(TM) GSK3beta Kinase Assay Kit is designed to measure GSK3beta (Glycogen Synthase Kinase 3 Beta) serine/threonine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified GSK3beta, kinase...
| Keywords: | GSK-3 beta, Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B, |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
827.00€
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Chemi-Verse(TM) ROS1 Kinase Assay Kit
Item number: BPS-82574
The Chemi-Verse(TM) ROS1 Kinase Assay Kit is designed to measure ROS1 (ROS Proto-Oncogene 1) tyrosine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified ROS1 kinase domain (amino acids...
| Keywords: | ROS1, MCF3, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, c-Ros receptor tyrosine kinase, Receptor tyrosine kinase c-ros... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
827.00€
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Chemi-Verse(TM) RET Kinase Assay Kit
Item number: BPS-82575
The Chemi-Verse(TM) RET Kinase Assay Kit is designed to measure RET (rearranged during transfection) tyrosine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified RET (amino acids 658-end), kinase...
| Keywords: | CDHF12, |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
827.00€
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Chemi-Verse(TM) HPK1 (MAP4K1) Kinase Assay Kit
Item number: BPS-82576
The Chemi-Verse(TM) HPK1 Kinase Assay Kit is designed to measure HPK1 (Hematopoietic progenitor kinase 1) serine/threonine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified HPK1 (amino acids...
| Keywords: | HPK1, MEKKK 1, MEK kinase kinase 1, MAPK/ERK kinase kinase kinase 1, Hematopoietic progenitor kinase, Mitogen-activated... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
827.00€
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Chemi-Verse(TM) STK3 (MST2) Kinase Assay Kit
Item number: BPS-82577
The Chemi-VerseTM STK3 (MST2) Kinase Assay Kit is designed to measure STK3 (serine/threonine-protein kinase 3), also known as MST2, tyrosine kinase activity for screening and profiling applications using ADP-GloTM as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified STK3,...
| Keywords: | Serine/threonine-protein kinase 3, Mammalian STE20-like protein kinase 2 (MST-2), STE20-like kinase MST2,... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
842.00€
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Chemi-Verse(TM) TYK2 Kinase Assay Kit
Item number: BPS-82578
The Chemi-VerseTM TYK2 Kinase Assay Kit is designed to measure TYK2 (Tyrosine Kinase 2) tyrosine kinase activity for screening and profiling applications using ADP-GloTM as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified TYK2, kinase substrate, ATP, and kinase assay...
| Keywords: | TYK2, Non-receptor tyrosine-protein kinase TYK2, |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
842.00€
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