Products from Bethyl Laboratories

Bethyl

Bethyl Laboratories is based in Montgomery, Texas, USA. Bethyl's mission is to be the premier provider of polyclonal antibodies to the research market. Bethyl will do this by continuous identfication of new and emerging proteins of interest through collaborations and scholarly searches. Bethyl Labs is unique in their end-to-end control of the entire antibody lifecycle. From the veterinary facilities to the development, production and validation labs, the Bethyl team focuses on delivering quality products. This attention to quality at every step and the integration across each stage of the process means scientists can rely on Bethyl antibodies.

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Anti-CD96 Recombinant Monoclonal
Anti-CD96 Recombinant Monoclonal

Item number: A700-065-T

Protein function: May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and...
Keywords: Anti-CD96, Anti-Cell surface antigen CD96, Anti-T-cell surface protein tactile, Anti-T cell-activated increased late...
Application: WB, IP, IHC, ICC
Reactivity: Human
From 125.00€ *
Review
Anti-PVR/CD155 Recombinant Monoclonal
Anti-PVR/CD155 Recombinant Monoclonal

Item number: A700-074-T

Protein function: Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger...
Keywords: Anti-PVR, Anti-PVS, Anti-CD155, Anti-NECL-5, Anti-Poliovirus receptor, Anti-Nectin-like protein 5
Application: WB, IHC, ICC
Reactivity: Human
From 125.00€ *
Review
Anti-GITR/TNFRSF18 Recombinant Monoclonal
Anti-GITR/TNFRSF18 Recombinant Monoclonal

Item number: A700-068-T

Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [The UniProt Consortium]
Keywords: Anti-AITR, Anti-CD357, Anti-TNFRSF18, Anti-Activation-inducible TNFR family receptor, Anti-Glucocorticoid-induced...
Application: WB, IP, IHC, ICC, IHC-IF
Reactivity: Human
From 125.00€ *
Review
Anti-Nectin-2/CD112 Recombinant Monoclonal
Anti-Nectin-2/CD112 Recombinant Monoclonal

Item number: A700-071-T

Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG,...
Keywords: Anti-HveB, Anti-HVEB, Anti-CD112, Anti-Nectin-2, Anti-Herpesvirus entry mediator B, Anti-Herpes virus entry mediator B,...
Application: WB, IHC, ICC, IHC-IF
Reactivity: Human
From 125.00€ *
Review
Anti-URB2
Anti-URB2

Item number: A305-875A-T

Keywords: Anti-URB2, Anti-KIAA0133, Anti-Unhealthy ribosome biogenesis protein 2 homolog
Application: WB, IP
Reactivity: Human
From 125.00€ *
Review
Anti-KIAA1549
Anti-KIAA1549

Item number: A305-877A-T

Keywords: Anti-KIAA1549, Anti-UPF0606 protein KIAA1549
Application: WB, IP
Reactivity: Human
From 125.00€ *
Review
Anti-CARD9
Anti-CARD9

Item number: A305-878A-T

Protein function: Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is at the crossroads of ITAM- tyrosine kinase and the Toll-like receptors (TLR) and NOD2 signaling pathways. Probably controls various innate immune...
Keywords: Anti-CARD9, Anti-hCARD9, Anti-Caspase recruitment domain-containing protein 9
Application: WB, IP
Reactivity: Human
From 125.00€ *
Review
Anti-FAM111B
Anti-FAM111B

Item number: A305-880A-T

Keywords: Anti-CANP, Anti-FAM111B, Anti-Protein FAM111B, Anti-Cancer-associated nucleoprotein
Application: WB
Reactivity: Human
From 125.00€ *
Review
Anti-SESN2
Anti-SESN2

Item number: A305-881A-T

Protein function: Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling (PubMed:18692468, PubMed:25263562, PubMed:25457612, PubMed:26449471, PubMed:26612684,...
Keywords: Anti-Sestrin-2, Anti-Hypoxia-induced gene
Application: WB, IP
Reactivity: Human
From 125.00€ *
Review
Anti-MafA Recombinant Monoclonal
Anti-MafA Recombinant Monoclonal

Item number: A700-067-T

Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Involved...
Keywords: Anti-MAFA, Anti-Transcription factor MafA, Anti-Transcription factor RIPE3b1, Anti-Pancreatic beta-cell-specific...
Application: WB, IHC, ICC, IHC-IF
Reactivity: Human, Mouse
From 125.00€ *
Review
Anti-USP7/HAUSP Recombinant Monoclonal
Anti-USP7/HAUSP Recombinant Monoclonal

Item number: A700-072-T

Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN, KMT2E/MLL5 and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148, PubMed:26678539). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the...
Keywords: Anti-HAUSP, Anti-Ubiquitin thioesterase 7, Anti-Deubiquitinating enzyme 7, Anti-Ubiquitin carboxyl-terminal hydrolase 7,...
Application: WB, IP, IHC, ICC
Reactivity: Human, Mouse
From 125.00€ *
Review
Anti-Bcl11a Recombinant Monoclonal
Anti-Bcl11a Recombinant Monoclonal

Item number: A700-073-T

Protein function: Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex. Repressor of fetal hemoglobin (HbF) level (PubMed:26375765). Involved in brain development (PubMed:27453576). Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and...
Keywords: Anti-EVI-9, Anti-CTIP1, Anti-BCL11A, Anti-BCL-11A, Anti-B-cell CLL/lymphoma 11A, Anti-Zinc finger protein 856, Anti-B-cell...
Application: WB, IP
Reactivity: Human
From 125.00€ *
Review
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