Products from Bethyl

Bethyl

Bethyl is based in Montgomery, Texas, USA. Bethyl's mission is to be the premier provider of polyclonal antibodies to the research market. Bethyl will do this by continuous identfication of new and emerging proteins of interest through collaborations and scholarly searches. Bethyl is unique in their end-to-end control of the entire antibody lifecycle. From the veterinary facilities to the development, production and validation labs, the Bethyl team focuses on delivering quality products. This attention to quality at every step and the integration across each stage of the process means scientists can rely on Bethyl antibodies.

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Anti-BIRC6/Apollon (IHC)
Anti-BIRC6/Apollon (IHC)

Item number: IHC-00124-T

Protein function: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-AF9 (IHC)
Anti-AF9 (IHC)

Item number: IHC-00125-T

Protein function: Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-CDX2 (IHC)
Anti-CDX2 (IHC)

Item number: IHC-00126-T

Protein function: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-4E-T(eIF4E-T) (IHC)
Anti-4E-T(eIF4E-T) (IHC)

Item number: IHC-00127-T

Protein function: Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism. [The UniProt Consortium]
Application: IHC, IHC-IF
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-CDT1 (IHC)
Anti-CDT1 (IHC)

Item number: IHC-00128-T

Protein function: Cooperates with CDC6 to promote the loading of the mini- chromosome maintenance complex onto chromatin to form the pre- replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-BAF57/SMARCE1 (IHC)
Anti-BAF57/SMARCE1 (IHC)

Item number: IHC-00129-T

Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-CBX5 (IHC)
Anti-CBX5 (IHC)

Item number: IHC-00130-T

Protein function: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-DDX17 (IHC)
Anti-DDX17 (IHC)

Item number: IHC-00131-T

Protein function: RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-DDX1 (IHC)
Anti-DDX1 (IHC)

Item number: IHC-00132-T

Protein function: Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-4EBP1 (IHC)
Anti-4EBP1 (IHC)

Item number: IHC-00133-T

Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-DDB1 (IHC)
Anti-DDB1 (IHC)

Item number: IHC-00134-T

Protein function: Required for DNA repair. Binds to DDB2 to form the UV- damaged DNA-binding protein complex (the UV-DDB complex). The UV- DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-DBC1/p30 DBC (IHC)
Anti-DBC1/p30 DBC (IHC)

Item number: IHC-00135-T

Protein function: Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A +...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Format: Antigen Affinity Purified
From 125.00€
Review
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