Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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Nampt (Visfatin/PBEF) (human) ELISA Kit
Item number: AG-45A-0006YEK-KI01
Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form...
| Keywords: | PBEF, NAMPT, Nampt, Visfatin, NAmPRTase, EC=2.4.2.12, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1,... |
| Application: | ELISA |
| Species reactivity: | human |
From 682.00€
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SB203580
Item number: AG-CR1-0030-M001
Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferative, PDK1 inhibitor, Anti-inflammatory, Review.
| Keywords: | 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole |
| Application: | p38 MAP kinase inhibitor |
| CAS | 152121-47-6 |
| MW: | 377,4 D |
From 39.00€
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MG-132
Item number: AG-CP3-0011-M005
Soluble in DMSO or ethanol. Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kappaB activation inhibitor through IkappaB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin...
| Keywords: | Z-Leu-Leu-Leu-CHO, Z-LLL-CHO, Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, MG132 |
| Application: | Proteasome inhibitor |
| CAS | 133407-82-6 |
| MW: | 476 D |
From 22.00€
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Anti-ADAM17 (human) (blocking), clone D1(A12)
Item number: AG-27B-6000PF-C100
Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor...
| Keywords: | Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
| Application: | FA (blocking) |
| Host: | Human |
| Species reactivity: | human |
572.00€
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Paclitaxel
Item number: AG-CN2-0045-M005
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
| Keywords: | Taxol, BMS 181339-01, NSC 125973 |
| Application: | Apoptosis Inducer |
| Host: | Taxus brevifolia |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
From 22.00€
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Progranulin (human) (rec.) (untagged)
Item number: AG-40A-0188Y-C050
Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
| Keywords: | GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Application: | Cell culture |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 74 kD |
From 215.00€
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Progranulin (human) ELISA Kit
Item number: AG-45A-0018YEK-KI01
Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Culture Supernatant , Plasma , Serum. Sensitivity: 32pg/ml. Range: 0.063 to 4ng/ml. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating...
| Keywords: | Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Application: | ELISA |
| Species reactivity: | human |
From 649.00€
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Latrunculin B
Item number: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Keywords: | LAT-B, NSC 339663 |
| Application: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
From 143.00€
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Anti-Caspase-1 (p10) (mouse), clone Casper-2
Item number: AG-20B-0044-C100
Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4...
| Keywords: | Interleukin-1 beta Convertase, IL-1BC, Interleukin-1 beta-converting Enzyme, ICE |
| Application: | WB |
| Host: | Mouse |
| Species reactivity: | mouse |
440.00€
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![Anti-Polyglutamate chain [Poly-E]](https://www.biomol.com/media/image/e5/f7/cf/AG-25B-0030-C050_200x200.png "Anti-Polyglutamate chain [Poly-E]")
Anti-Polyglutamate chain [Poly-E]
Item number: AG-25B-0030-C050
Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and...
| Keywords: | Anti-Poly-E, pAb (IN105), Anti-Poly-Glu |
| Application: | WB, ICC |
| Host: | Rabbit |
| Species reactivity: | broad |
429.00€
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Thapsigargin (high purity)
Item number: AG-CN2-0003-M001
Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
| Application: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650,8 D |
From 77.00€
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Rapamycin
Item number: AG-CN2-0025-M001
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
| Keywords: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Application: | mTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| CAS | 53123-88-9 |
| MW: | 914,2 D |
From 28.00€
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