Products from Abgent

Abgent

Abgent was founded in 2001. The goal of Abgent is to provide genome wide antibody coverage. Thus you find - for example - an Abgent antibody for every human kinase. With state of the art production facilities, Abgent's scientists now manufacture over 4,000 antibodies per year. The antibodies are rigorously validated and optimized to ensure quality results.

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Anti-MKNK1 (monoclonal) (M06)
Anti-MKNK1 (monoclonal) (M06)

Item number: WA-AT2872a

Clear, colorless solution in phosphate buffered saline, pH 7.2 . Protein function: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap. [The UniProt Consortium]
Application: WB, IHC, IF, ELISA
Antibody Type: Monoclonal
Host: Mouse
Reactivity: Human
MW: 51342 D
539.00€
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Anti-OCLN (monoclonal) (M01)
Anti-OCLN (monoclonal) (M01)

Item number: WA-AT3143a

Clear, colorless solution in phosphate buffered saline, pH 7.2 . Protein function: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. [The UniProt Consortium]
Application: WB, IF, ELISA
Antibody Type: Monoclonal
Host: Mouse
Reactivity: Human
MW: 59144 D
539.00€
Review
50% OFF
Anti-Hoxa1 (Center) (mouse)
Anti-Hoxa1 (Center) (mouse)

Item number: WA-AW5236.400

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. Protein function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on...
Application: WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Mouse
Format: Affinity Purified
188.00€ From 94.00€
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Anti-Mouse TRIAD3A (N-Terminal)
Anti-Mouse TRIAD3A (N-Terminal)

Item number: WA-ABD10005.50

Protein function: Acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down-regulates activation of NF-kappa-B, IRF3 activation and IFNB...
Application: IHC (paraffin), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Mouse
Format: Purified
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Anti-TSC1
Anti-TSC1

Item number: WA-ABD10006.50

Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR...
Application: IHC (frozen), IHC (paraffin), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Rat,Mouse
Format: Purified
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Anti-AES (C-Terminal)
Anti-AES (C-Terminal)

Item number: WA-ABD10007.50

Protein function: Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. [The UniProt Consortium]
Application: IHC (frozen), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse,Rat
Format: Purified
Please request pricing for this article.
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Anti-Beclin-1 (N-Terminal)
Anti-Beclin-1 (N-Terminal)

Item number: WA-ABD10008.50

Protein function: Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3- C2 in maturation of autophagosomes and endocytosis. Involved...
Application: FC, IHC (paraffin), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse,Rat
Format: Purified
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Anti-IRE1p (C-Terminal)
Anti-IRE1p (C-Terminal)

Item number: WA-ABD10009.50

Protein function: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. [The UniProt...
Application: IHC (frozen), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Rat,Mouse
Format: Purified
Please request pricing for this article.
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Anti-Human NOD2 (C-Terminal)
Anti-Human NOD2 (C-Terminal)

Item number: WA-ABD10010.50

Protein function: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the...
Application: IHC (frozen), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Purified
Please request pricing for this article.
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Anti-Noxa
Anti-Noxa

Item number: WA-ABD10011.50

Protein function: Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on...
Application: IHC (paraffin), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Mouse, Human,Rat
Format: Purified
Please request pricing for this article.
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Anti-Human CD283
Anti-Human CD283

Item number: WA-ABD10012.50

Protein function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B...
Application: IHC (frozen), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Format: Purified
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Anti-Human CD286
Anti-Human CD286

Item number: WA-ABD10013.50

Protein function: Participates in the innate immune response to Gram- positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides (PubMed:20037584). In response to diacylated lipopeptides, forms the activation cluster TLR2:TLR6:CD14:CD36, this cluster triggers signaling from the cell surface and subsequently is targeted...
Application: IHC (frozen), WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Purified
Please request pricing for this article.
Review
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