- Search results for Cay13748-%25
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6 products were found matching "Cay13748-%25"!
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Item number: Cay37481-25
SP-8356 is a derivative of (1S)-(-)-verbenone and an inhibitor of CD147, also known as extracellular matrix metalloproteinase (MMP) inducer (EMMPRIN) and previously known as tumor cell-derived collagenase stimulatory factor (TCSF). It inhibits the dimerization of CD147 and the protein-protein interaction between...
Keywords: | (1S,5R)-4-[(1E)-2-(3,4-dihydroxy-5-methoxyphenyl)ethenyl]-6,6-dimethyl-bicyclo[3.1.1]hept-3-en-2-one |
Application: | CD147 inhibitor |
CAS | 1454885-45-0 |
MW: | 300.4 D |
From 82.00€
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Item number: Cay18374-25
L189 is a competitive inhibitor of DNA ligases I, III, and IV (IC50s = 5, 9, and 5 µM, respectively). It blocks DNA binding (Ki = 5 µM for DNA ligase I), increasing the cytotoxicity of DNA-damaging agents, including ionizing radiation. L189 preferentially inhibits the interaction of the ligase with damaged DNA,...
Keywords: | 6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone |
Application: | DNA ligase I, III, IV inhibitor |
CAS | 64232-83-3 |
MW: | 246.3 D |
From 115.00€
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Item number: Cay18743-25
Cimetidine is a histamine H2 receptor antagonist (Ki = 0.6 µM). It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1.2 µM). Cimetidine inhibits histamine-induced acid secretion from isolated bullfrog gastric mucosa (IC50 = 16 µM). In vivo, it...
Keywords: | NSC 335308, SKF 92334, N-cyano-N''-methyl-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-guanidine |
Application: | H2-receptor antagonist |
CAS | 51481-61-9 |
MW: | 252.3 D |
From 48.00€
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Item number: Cay13248-25
L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood-brain barrier. It is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. Formulations containing L-DOPA have been used in stroke...
Keywords: | 3,4-Dihydroxyphenylalanine, Levodopa, 3-hydroxy-L-tyrosine |
Application: | Neuropharmacological agent |
CAS | 59-92-7 |
MW: | 197.2 D |
From 26.00€
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Item number: Cay13648-25
Alfuzosin is a post-synaptic alpha1-adrenergic receptor antagonist commonly used to improve lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It displays high-affinity with non-selectivity for the three known human alpha1 adrenoceptors (pKi = 8.0, 8.0, and 8.5 for alpha1A, alpha1B, and...
Keywords: | SL 77499-10, Uroxatral, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide,... |
Application: | alpha1-adrenergic receptor antagonist |
CAS | 81403-68-1 |
MW: | 425.9 D |
From 60.00€
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Item number: Cay37148-25
PEG(2000)-DSPE is a PEGylated form of 1,2-distearoyl-sn-glycero-3-PE (DSPE, Cay-15095). It has been used in the generation of micelles and in combination with other lipids in the formation of liposomes. Liposomes containing PEG(2000)-DSPE and encapsulating the DNA topoisomerase inhibitor doxorubicin (Cay-15007) and...
Keywords: | PEG(2000)-1,2-DSPE, PEG2000-DSPE, Polyethylene Glycol-2000-1,2-Distearoyl-sn-glycero-3-PE, Polyethylene... |
Application: | DSPE PEGylated form |
MW: | 2810.4 D |
From 114.00€
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