6 products were found matching "Cay13748-%25"!

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SP-8356
SP-8356

Item number: Cay37481-25

SP-8356 is a derivative of (1S)-(-)-verbenone and an inhibitor of CD147, also known as extracellular matrix metalloproteinase (MMP) inducer (EMMPRIN) and previously known as tumor cell-derived collagenase stimulatory factor (TCSF). It inhibits the dimerization of CD147 and the protein-protein interaction between...
Keywords: (1S,5R)-4-[(1E)-2-(3,4-dihydroxy-5-methoxyphenyl)ethenyl]-6,6-dimethyl-bicyclo[3.1.1]hept-3-en-2-one
Application: CD147 inhibitor
CAS 1454885-45-0
MW: 300.4 D
From 82.00€ *
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L189
L189

Item number: Cay18374-25

L189 is a competitive inhibitor of DNA ligases I, III, and IV (IC50s = 5, 9, and 5 µM, respectively). It blocks DNA binding (Ki = 5 µM for DNA ligase I), increasing the cytotoxicity of DNA-damaging agents, including ionizing radiation. L189 preferentially inhibits the interaction of the ligase with damaged DNA,...
Keywords: 6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone
Application: DNA ligase I, III, IV inhibitor
CAS 64232-83-3
MW: 246.3 D
From 115.00€ *
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Cimetidine
Cimetidine

Item number: Cay18743-25

Cimetidine is a histamine H2 receptor antagonist (Ki = 0.6 µM). It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1.2 µM). Cimetidine inhibits histamine-induced acid secretion from isolated bullfrog gastric mucosa (IC50 = 16 µM). In vivo, it...
Keywords: NSC 335308, SKF 92334, N-cyano-N''-methyl-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-guanidine
Application: H2-receptor antagonist
CAS 51481-61-9
MW: 252.3 D
From 48.00€ *
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L-DOPA
L-DOPA

Item number: Cay13248-25

L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood-brain barrier. It is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. Formulations containing L-DOPA have been used in stroke...
Keywords: 3,4-Dihydroxyphenylalanine, Levodopa, 3-hydroxy-L-tyrosine
Application: Neuropharmacological agent
CAS 59-92-7
MW: 197.2 D
From 26.00€ *
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Alfuzosin (hydrochloride)
Alfuzosin (hydrochloride)

Item number: Cay13648-25

Alfuzosin is a post-synaptic alpha1-adrenergic receptor antagonist commonly used to improve lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It displays high-affinity with non-selectivity for the three known human alpha1 adrenoceptors (pKi = 8.0, 8.0, and 8.5 for alpha1A, alpha1B, and...
Keywords: SL 77499-10, Uroxatral, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide,...
Application: alpha1-adrenergic receptor antagonist
CAS 81403-68-1
MW: 425.9 D
From 60.00€ *
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PEG(2000)-DSPE
PEG(2000)-DSPE

Item number: Cay37148-25

PEG(2000)-DSPE is a PEGylated form of 1,2-distearoyl-sn-glycero-3-PE (DSPE, Cay-15095). It has been used in the generation of micelles and in combination with other lipids in the formation of liposomes. Liposomes containing PEG(2000)-DSPE and encapsulating the DNA topoisomerase inhibitor doxorubicin (Cay-15007) and...
Keywords: PEG(2000)-1,2-DSPE, PEG2000-DSPE, Polyethylene Glycol-2000-1,2-Distearoyl-sn-glycero-3-PE, Polyethylene...
Application: DSPE PEGylated form
MW: 2810.4 D
From 114.00€ *
Review