Anti-Triad1

Anti-Triad1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-896A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A302-896A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins... more
Product information "Anti-Triad1"
Protein function: E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin- conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets. The initial ubiquitin is then elongated. E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655). Mediates 'Lys-6', 'Lys-48'-and 'Lys- 63'-linked polyubiquitination (PubMed:16118314, PubMed:17646546, PubMed:19340006). May play a role in myelopoiesis (PubMed:19340006). [The UniProt Consortium]
Keywords: Anti-ARI2, Anti-ARI-2, Anti-ARIH2, Anti-HT005, Anti-Triad1 protein, Anti-Protein ariadne-2 homolog, Anti-E3 ubiquitin-protein ligase ARIH2, Anti-RING-type E3 ubiquitin transferase ARIH2
Supplier: Bethyl Laboratories
Supplier-Nr: A302-896A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, X. laevis, X. tropicalis, chicken, turkey, bovine, dog, horse, rabbit, guinea pig, swine, panda, orangutan, rhesus monkey, gorilla, chimpanzee, west indian ocean coelacanth, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-896A maps to a region between residue 453 and 493 of human All-trans Retinoic Acid Inducible RING Finger using the numbering given in entry NP_006312.1 (GeneID 10425).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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