Cytokines

In this category, you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony-stimulating factors (CSF), tumor necrosis factors (TNF), chemokines, and growth factors for your research applications. Cytokines regulate the differentiation, proliferation, and activity of cells. For this reason, they are often used in cell culture experiments. Cytokine products are also used as controls in immunoassays. Information, such as the specific activity of a cytokine, the amino acid sequence, results of a monocyte activation tests, and more can be found in the datasheet of each product.

In this category, you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony-stimulating factors (CSF), tumor necrosis factors (TNF),... read more »
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Cytokines

In this category, you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony-stimulating factors (CSF), tumor necrosis factors (TNF), chemokines, and growth factors for your research applications. Cytokines regulate the differentiation, proliferation, and activity of cells. For this reason, they are often used in cell culture experiments. Cytokine products are also used as controls in immunoassays. Information, such as the specific activity of a cytokine, the amino acid sequence, results of a monocyte activation tests, and more can be found in the datasheet of each product.

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Epidermal Growth Factor, human recombinant (rHuEGF)
Epidermal Growth Factor, human recombinant (rHuEGF)

Item number: 50349.100

Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate...
Keywords: Urogastrone, URG, EGF
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 6.2 kD
From 94.00€ *
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Interleukin-2, human recombinant (rHuIL-2)
Interleukin-2, human recombinant (rHuIL-2)

Item number: 50442.50

Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org)...
Keywords: T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 15.4 kD
From 94.00€ *
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Bone Morphogenetic Protein-2, human recombinant (rHuBMP-2)
Bone Morphogenetic Protein-2, human recombinant (rHuBMP-2)

Item number: 54299.10

Induces cartilage and bone formation. (www.uniprot.org) Produced in E.coli. Homodimeric, non-glycosylated polypeptide chain containing 115 amino acids. The ED50 as determined by the cytolysis of MC3T3-E1 cells is less then 50 ng/ml.
Keywords: BMP-2, BMP2A
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 26 kD
From 94.00€ *
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Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic)
Fibroblast Growth Factor basic, human recombinant...

Item number: 50361.50

Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and...
Keywords: Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 17.2 kD
From 94.00€ *
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Tumor Necrosis Factor alpha, human recombinant (rHuTNF-a)
Tumor Necrosis Factor alpha, human recombinant (rHuTNF-a)

Item number: 50435.10

Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral...
Keywords: TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 17.5 kD
From 94.00€ *
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Granulocyte Macrophage Colony Stimulating Factor, human recombinant (rHuGM-CSF)
Granulocyte Macrophage Colony Stimulating Factor, human...

Item number: 50449.20

Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 127 amino acids. The ED50 as determined by...
Keywords: CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim, MGC131935, MGC138897
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 14477 D
From 94.00€ *
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Interferon gamma, human recombinant (rHuIFN-gamma)
Interferon gamma, human recombinant (rHuIFN-gamma)

Item number: 51564.100

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects...
Keywords: Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI, IFN-gamma
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 17 kD
From 94.00€ *
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Macrophage Colony Stimulating  Factor, human recombinant (rHuM-CSF)
Macrophage Colony Stimulating Factor, human recombinant...

Item number: 60530.10

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a...
Keywords: Macrophage Colony Stimulating Factor, CSF-1, Lanimostim, MCSF, MGC31930, M-CSF
Application: Cell Culture
Expressed in: E.coli
Origin: human
MW: 37.1 kD
From 94.00€ *
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Interleukin-21, human recombinant (rHuIL-21)
Interleukin-21, human recombinant (rHuIL-21)

Item number: 87340.10

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B-...
Keywords: Za11, IL-21
Application: Cell Culture
Expressed in: E.coli
Origin: human
MW: 15,4 kD
From 94.00€ *
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Interleukin-6, human recombinant (rHuIL-6)
Interleukin-6, human recombinant (rHuIL-6)

Item number: 50436.20

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells...
Keywords: IFN-b2, B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2, Interferon beta-2,...
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 21 kD
From 94.00€ *
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Interleukin-3, mouse recombinant (rmIL-3)
Interleukin-3, mouse recombinant (rmIL-3)

Item number: 50443.10

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated...
Keywords: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor, IL-3, MGC79398, MGC79399
Application: Cell culture
Expressed in: E.coli
Origin: mouse
MW: 15100.00 D
From 94.00€ *
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Vascular Endothelial Growth Factor, human recombinant (rHuVEGF-CHO)
Vascular Endothelial Growth Factor, human recombinant...

Item number: 94900.10

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds...
Keywords: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609
Application: Cell biology studies
Expressed in: Hamster cells
Origin: human
MW: 42000.00 D
From 94.00€ *
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