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Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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Item number: CHI-MF-11135-C025
The mouse IL-35 complex composed of the Ebi3 subunit (aa 23-228) and the IL-12a (p35) subunit (aa 23-215) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: | Interleukin-35, Il12a, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation... |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | mouse |
From 314.00€
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Item number: CHI-HR-20618-C010
Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting...
Keywords: | Interleukin-18, Interferon-gamma-inducing Factor, IGIF, IL-1gamma, IL1F4 |
Application: | Bioassays |
Expressed in: | E.coli |
Origin: | human |
MW: | ~18 kD |
From 171.00€
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Item number: CHI-HF-21035-C025
The human IL-35 complex composed of the Ebi3 subunit (aa 21-229) and the IL-12a (p35) subunit (aa 57-253) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: | Interleukin-35, NKSF1, IL12A, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory... |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
286.00€
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Item number: CHI-HF-210GAL9-C050
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
Keywords: | Gal-9, LGALS9, Ecalectin, Galectin-9, Tumor antigen HOM-HD-21, Gal-9, Ecalectin, TIM3L, TIM-3 Ligand, T Cell... |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human |
391.00€
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Item number: CHI-HF-211T4-C100
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
Keywords: | TIM4, TIMD4, TIM-4, TIMD-4, T-cell membrane protein 4, T-cell immunoglobulin mucin receptor 4, T-cell immunoglobulin and... |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human |
MW: | ~80 kD |
523.00€
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Item number: CHI-HF-210PDL1-C100
The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating...
Keywords: | B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
429.00€
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Item number: CHI-HF-220PDL1-C100
The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD274 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Programmed...
Keywords: | B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
429.00€
*
Item number: CHI-HR-200CD27-C050
Human CD27 (aa 21-192) is fused at the C-terminus to a His-tag. CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity...
Keywords: | T14, CD27, TNFRSF7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor... |
Application: | Bioassays |
Expressed in: | E.coli |
Origin: | human |
380.00€
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Item number: CHI-MF-11123-C050
The mouse IL-23 complex composed of the p40 subunit (aa 23-335) and the p19 subunit (aa 20-196) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. 0 Interleukin-23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19...
Keywords: | Interleukin-23, Il12b, IL-12B, CLMF p40, IL-12 subunit p40, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation... |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | mouse |
418.00€
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Item number: CHI-HF-201PDL1-C100
Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of two ligands for programmed death 1 (PD-1), a member of the CD28 family of immunoreceptors. CD274 is...
Keywords: | B7H1, PD-L1, CD274, B7-H1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
Application: | FA |
Expressed in: | Human cells |
Origin: | human |
MW: | ~35 kD |
429.00€
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Item number: CHI-HF-210B7H3-C100
The extracellular domain of human CD276 [B7-H3] (aa 29-245) is fused to the N-terminus of the Fc region of human IgG1. CD276 (B7-H3) is a member of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T cell response. B7 family molecules, which are expressed on antigen-presenting...
Keywords: | B7H3, B7-H3, CD276, PSEC0249, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
429.00€
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Item number: CHI-HF-210IG1-C100
This product should be used as the control protein for activity tests of fusion proteins including human target proteins and human IgG-Fc domains.
Keywords: | IGHG1, Ig gamma-1 chain C region, |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human |
MW: | ~26 kD |
391.00€
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